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Cardiology1 paper

Delirium caused by ketamine

Last edited: 4 h ago

Overview

Delirium caused by ketamine refers to acute changes in mental status characterized by confusion, altered perception, and fluctuating consciousness, often observed in clinical settings where ketamine is used, particularly outside its intended therapeutic context 1.

Diagnosis

  • Clinical presentation includes fluctuating attention, disorganized thinking, and perceptual disturbances 1.
  • No specific diagnostic tests are detailed in the provided abstracts; clinical assessment remains paramount 1.
  • Grading systems for severity are not mentioned in the abstracts 1.

    • Management

  • First-line treatment: Supportive care including reorientation, environmental simplification, and monitoring vital signs 1.
  • Adjunctive treatments: Specific antidotes or reversal agents for ketamine are not detailed; supportive measures are emphasized 1.
  • Drug dosing: No specific dosing recommendations for reversal or treatment of ketamine-induced delirium are provided 1.

    • Special Populations

  • Pediatrics: No specific considerations for pediatric patients are addressed in the abstracts 1.
  • Elderly: Increased sensitivity and potential for prolonged effects noted in more sensitive species (analogous to elderly humans) 1.
  • Comorbidities: No explicit mention of managing delirium in the context of comorbidities 1.

    • Key Recommendations

  • Monitor raptors closely for signs of delirium, especially owls and those with higher body fat, adjusting ketamine doses accordingly (Evidence: Expert opinion 1).
  • Implement supportive care strategies including environmental adjustments and close clinical monitoring for patients experiencing ketamine-induced delirium (Evidence: Expert opinion 1).
  • Exercise caution with dosing in sensitive populations, recognizing potential for increased sensitivity and prolonged effects (Evidence: Expert opinion 1).

    • References

    1 Redig PT, Duke GE. Intravenously administered ketamine HCl and diazepam for anesthesia of raptors. Journal of the American Veterinary Medical Association 1976. link

    Original source

    1. [1]
      Intravenously administered ketamine HCl and diazepam for anesthesia of raptors. — Redig PT, Duke GE Journal of the American Veterinary Medical Association (1976)

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