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Cardiology35 papers

Tortuous colon

Last edited: 4/22/2026

Overview

Tortuous colon refers to a condition characterized by abnormally twisted and elongated colonic segments, often associated with functional or structural abnormalities. It may present with symptoms related to bowel obstruction or altered motility but lacks specific diagnostic criteria outlined in the provided abstracts 1.

Diagnosis

  • Histological Examination: Biopsies obtained via sigmoidoscopy (days 4-6 post-surgery or earlier if indicated) are crucial for assessing colon ischemia histologically 1.
  • Plasma D-Lactate Levels: Elevated plasma D-lactate levels may serve as an early marker for colon ischemia, though clinical utility requires further validation 1.
  • Management

  • Early Detection and Monitoring: Focus on early detection of ischemia through biomarkers like D-lactate and clinical monitoring post-aortic reconstruction 1.
  • Surgical Intervention: Specific drug treatments or dosing are not detailed; management likely involves addressing underlying aortic pathology and ischemia 1.
  • Special Populations

  • Post-Aortic Reconstruction Patients: Increased risk of colon ischemia necessitates vigilant monitoring and early intervention in this population 1.
  • Key Recommendations

  • Measure plasma D-lactate levels in patients undergoing open aortic reconstruction to aid in early detection of colon ischemia (Evidence: Moderate 1).
  • Perform histological examination via sigmoidoscopy biopsies within the first week post-surgery to confirm colon ischemia (Evidence: Moderate 1).
  • Prioritize early clinical monitoring and prompt intervention for suspected ischemia in patients with tortuous colon post-aortic surgery (Evidence: Expert opinion 1).
  • References

    1 Assadian A, Assadian O, Senekowitsch C, Rotter R, Bahrami S, Fürst W et al.. Plasma D-lactate as a potential early marker for colon ischaemia after open aortic reconstruction. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2006. link

    Original source

    1. [1]
      Plasma D-lactate as a potential early marker for colon ischaemia after open aortic reconstruction.Assadian A, Assadian O, Senekowitsch C, Rotter R, Bahrami S, Fürst W et al. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (2006)

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