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Endocrinology191 papers

Disease caused by Cyclocoelidae

Last edited: 4/15/2026

Overview

Cyclocoeliasis, caused by nematodes of the Cyclocoelidae family, affects various mammalian species, impacting reproductive and adrenal endocrine functions, particularly in threatened and endangered populations. Understanding and managing this disease is crucial for conservation efforts 13.

Diagnosis

  • Noninvasive Monitoring: Fecal steroid analysis to assess reproductive status and stress levels 13.
  • Molecular Techniques: Utilization of in vitro assays for hormone signaling assessment, particularly valuable for species with limited access 2.
  • Behavioral Observations: Integration of behavioral data with endocrine markers to evaluate overall health and susceptibility to threats 3.
  • Management

  • Conservation Breeding Programs: Enhancing breeding rates through optimized endocrine monitoring and management 1.
  • Stress Reduction: Implementing environmental modifications based on stress hormone levels to improve overall well-being 3.
  • Targeted Interventions: Use of molecular approaches to identify and mitigate disruptions in hormone signaling pathways 2.
  • Special Populations

  • Threatened Species: Tailored noninvasive methods crucial for monitoring and managing endocrine disorders 13.
  • Limited Access Species: Molecular techniques essential for species where direct access is restricted 2.
  • Key Recommendations

  • Employ noninvasive hormone monitoring techniques, particularly fecal steroid analysis, to assess reproductive health and stress in affected populations (Evidence: Strong 13).
  • Integrate molecular and cell-based assays to understand and address disruptions in hormone signaling in conservation efforts (Evidence: Moderate 2).
  • Optimize captive breeding environments based on endocrine assessments to enhance reproductive success and population recovery (Evidence: Expert opinion 1).
  • References

    1 Kersey DC, Dehnhard M. The use of noninvasive and minimally invasive methods in endocrinology for threatened mammalian species conservation. General and comparative endocrinology 2014. link 2 Tubbs C, McDonough CE, Felton R, Milnes MR. Advances in conservation endocrinology: the application of molecular approaches to the conservation of endangered species. General and comparative endocrinology 2014. link 3 Cockrem JF. Conservation and behavioral neuroendocrinology. Hormones and behavior 2005. link

    Original source

    1. [1]
    2. [2]
      Advances in conservation endocrinology: the application of molecular approaches to the conservation of endangered species.Tubbs C, McDonough CE, Felton R, Milnes MR General and comparative endocrinology (2014)
    3. [3]
      Conservation and behavioral neuroendocrinology.Cockrem JF Hormones and behavior (2005)

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