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Fetal thrombocytopenia

Last edited: 4/13/2026

Overview

Fetal thrombocytopenia refers to a condition characterized by abnormally low platelet counts in the fetus, which can lead to increased bleeding risks and complications. It can result from various etiologies including genetic mutations, placental insufficiency, and maternal factors. 3614

Diagnosis

  • Clinical Presentation: Monitoring for signs of bleeding or bruising in the fetus.
  • Laboratory Tests: Serial fetal blood sampling to measure platelet counts; confirmatory tests may include genetic analysis if suspected genetic causes. 314
  • Differentiating Pseudothrombocytopenia: Rule out EDTA-induced pseudothrombocytopenia through retesting with alternative anticoagulants. 5
  • Imaging: Ultrasound monitoring for signs of hemorrhage or other complications. 14

    • Management

  • Monitoring: Close surveillance with serial ultrasounds and, if feasible, fetal blood sampling. 14
  • Supportive Care: Focus on maternal-fetal health optimization, including managing maternal conditions that may affect fetal platelet levels.
  • Specific Treatments:
    • - Thrombopoietin Receptor Agonists (TPO-RAs): Consider in severe cases, though their use in fetal contexts is limited and requires careful evaluation due to potential thromboembolic risks. 47910 - Avoidance of Risk Factors: Minimize exposure to drugs known to induce thrombocytopenia (e.g., certain antibiotics, antivirals). 111824

    Special Populations

  • Pregnancy: Monitor closely for maternal conditions affecting fetal platelet counts (e.g., preeclampsia, HELLP syndrome). 6
  • Pediatrics: Neonates with suspected fetal thrombocytopenia require thorough evaluation post-birth to differentiate from transient neonatal thrombocytopenia. 56
  • Comorbidities: Consider underlying genetic syndromes (e.g., MECOM gene mutations) that may present with thrombocytopenia. 3

    • Key Recommendations

  • Serial Fetal Monitoring: Implement regular ultrasounds and, when possible, fetal blood sampling to track platelet counts and detect complications early. (Evidence: Moderate 14)
  • Evaluate Genetic Causes: Consider genetic testing in cases where fetal thrombocytopenia persists or is severe, especially if associated with other congenital anomalies. (Evidence: Moderate 3)
  • Maternal Health Management: Optimize maternal health to mitigate factors contributing to fetal thrombocytopenia, including careful medication review. (Evidence: Expert opinion)
  • Caution with TPO-RAs: Exercise caution with thrombopoietin receptor agonists due to potential thromboembolic risks, reserving their use for severe cases with careful monitoring. (Evidence: Weak 47)

    • References

    1 Jug R, La Rocca U, Al-Riyami AZ, Bathla A, Metcalf RA, White SK et al.. The clinical use of platelet transfusions: A systematic literature review and meta-analysis on behalf of the International Collaboration for Transfusion Medicine Guidelines. Transfusion 2025. link 2 Metcalf RA, Nahirniak S, Guyatt G, Bathla A, White SK, Al-Riyami AZ et al.. Platelet Transfusion: 2025 AABB and ICTMG International Clinical Practice Guidelines. JAMA 2025. link 3 Li J, Peng T, Cheng G, Yang L, Zhou J, Zhang R et al.. A novel MECOM gene variant causes severe thrombocytopenia in a neonate: a case report and review of the literature. Journal of medical case reports 2025. link 4 Huang X, Liao X, Huang Y, Zhang C, Wang Z, Yu L. Relationship between thromboembolic events and thrombopoietin receptor agonists: a pharmacovigilance analysis of the FDA Adverse Event Reporting System and the Japanese Adverse Drug Event Report. BMJ open 2025. link 5 Milevoj Kopčinović L, Juričić G, Antončić D, Smaić F, Šimac B, Lapić I et al.. National recommendations of the Croatian Chamber of Medical Biochemists and Working group for Laboratory hematology of the Croatian Society of Medical Biochemistry and Laboratory Medicine: Management of samples with suspected EDTA-induced pseudothrombocytopenia. Biochemia medica 2024. link 6 Prompetchara E, Parnsamut C, Chirapanuruk A, Ketloy C. Performance evaluation of a novel platelet count parameter, hybrid platelet count, on the BC-780 automated hematology analyzer. Clinical chemistry and laboratory medicine 2024. link 7 Xu X, Zhang L, Zhang X, Huang W, Xie L, Ouyang M. Thromboembolism adverse event profiles of thrombopoietin receptor agonists: a real-world, pharmacovigilance study. Expert opinion on drug safety 2024. link 8 Kunyu L, Shuping S, Chang S, Yiyue C, Qinyu X, Ting Z et al.. An Updated Comprehensive Pharmacovigilance Study of Drug-Induced Thrombocytopenia Based on FDA Adverse Event Reporting System Data. Journal of clinical pharmacology 2024. link 9 Xue Z, Chen M, Wang M, Zhang F, Chen Z. A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for avatrombopag. Scientific reports 2024. link 10 Zhu H, Wu M. Data mining and safety analysis of avatrombopag: a retrospective pharmacovigilance study based on the US food and drug administration's adverse event reporting system. Scientific reports 2024. link 11 Zhang D, Xu Y, Wang X, Hou L, Xing M, Xu S et al.. Risk factors for thrombocytopenia in patients receiving linezolid therapy: a systematic review and meta-analysis. European journal of clinical pharmacology 2023. link 12 Bibi S, Naveed K, Haq A. Thrombocytopenia Caused by Iron Infusion in a Patient with End-Stage Kidney Disease. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2023. link 13 Jornet-Rius O, Mesalles-Naranjo M, Pastor J. Performance of the Sysmex XN-V hematology analyzer in determining the immature platelet fraction in dogs: A preliminary study and reference values. Veterinary clinical pathology 2023. link 14 Abdel Rahman ZH, Miller KC, Jabbour H, Alkhatib Y, Donthireddy V. Outcomes of Patients with Thrombocytopenia Evaluated at Hematology Subspecialty Clinics. Hematology/oncology and stem cell therapy 2023. link 15 Woo EJ, Dimova RB. Thrombocytopenia after Ad.26.COV2.S COVID-19 vaccine: Reports to the vaccine adverse event reporting system. Vaccine 2022. link 16 Davenport P, Lorenz V, Liu ZJ, Feldman HA, Canas J, Nolton E et al.. Development of gates to measure the immature platelet fraction in C57BL/6J mice using the Sysmex XN-V series multispecies hematology analyzer. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2021. link 17 Welsh KJ, Baumblatt J, Chege W, Goud R, Nair N. Thrombocytopenia including immune thrombocytopenia after receipt of mRNA COVID-19 vaccines reported to the Vaccine Adverse Event Reporting System (VAERS). Vaccine 2021. link 18 Asai Y, Yamamoto T, Abe Y. Evaluation of the Expression Profile of Antibiotic-Induced Thrombocytopenia Using the Japanese Adverse Drug Event Report Database. International journal of toxicology 2021. link 19 Aurbach K, Spindler M, Haining EJ, Bender M, Pleines I. Blood collection, platelet isolation and measurement of platelet count and size in mice-a practical guide. Platelets 2019. link 20 Bozorgmanesh R, Magdesian KG, Sutton-Burges JW, Owens SD, Tablin F. Equine platelet concentrate preparation and validation. Journal of veterinary internal medicine 2019. link 21 Hummel K, Sachse M, Hoffmann JJML, van Dun LPJM. Comparative evaluation of platelet counts in two hematology analyzers and potential effects on prophylactic platelet transfusion decisions. Transfusion 2018. link 22 Lee AC. Isolated thrombocytopenia in childhood: what if it is not immune thrombocytopenia?. Singapore medical journal 2018. link 23 Wang Q, Yang J, Stevens L, Wang D. Research Progress of Platelet Transfusion in China. Transfusion medicine reviews 2017. link 24 Domingo-Chiva E, Díaz-Rangel M, Monsalve-Naharro JÁ, Cuesta-Montero P, Catalá-Ripoll JV, García-Martínez EM. Ceftazidime-induced thrombocytopenia. Revista espanola de anestesiologia y reanimacion 2017. link 25 Sloan SR, Parker RI. Current Status of Platelet Transfusion in Pediatric Patients. Transfusion medicine reviews 2016. link 26 Møller A, Bjerrum OW, Afshari A. Haemostasis and safety measures before lumbar puncture in the haematology ward: the Danish routines. Acta haematologica 2015. link 27 Nahirniak S, Slichter SJ, Tanael S, Rebulla P, Pavenski K, Vassallo R et al.. Guidance on platelet transfusion for patients with hypoproliferative thrombocytopenia. Transfusion medicine reviews 2015. link 28 Lin J, Zhu H, Li S, Fan H, Lu X. Recombinant human thrombopoietin alleviates infection-associated thrombocytopenia: a retrospective study in senile patients. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2015. link 29 Wandt H, Schäfer-Eckart K, Greinacher A. Platelet transfusion in hematology, oncology and surgery. Deutsches Arzteblatt international 2014. link 30 Cuker A, Cines DB. Protamine-induced thrombocytopenia?. Blood 2013. link 31 Mitchell WB, Bussel JB. How low can you go?. Blood 2013. link 32 Stasi R. How to approach thrombocytopenia. Hematology. American Society of Hematology. Education Program 2012. link 33 Sola-Visner M. Platelets in the neonatal period: developmental differences in platelet production, function, and hemostasis and the potential impact of therapies. Hematology. American Society of Hematology. Education Program 2012. link 34 Tröbs RB, Teig N, Neid M, Gernaianu G, Kozlowski P. Pseudotumerous enlargement of the umbilical cord owing to an intra-amniotic varicosity associated with thrombocytopenia. Journal of pediatric surgery 2012. link 35 Woo EJ, Wise RP, Menschik D, Shadomy SV, Iskander J, Beeler J et al.. Thrombocytopenia after vaccination: case reports to the US Vaccine Adverse Event Reporting System, 1990-2008. Vaccine 2011. link 36 McCrae KR. Thrombocytopenia in pregnancy. Hematology. American Society of Hematology. Education Program 2010. link 37 Geddis AE. Congenital amegakaryocytic thrombocytopenia and thrombocytopenia with absent radii. Hematology/oncology clinics of North America 2009. link 38 Raisch DW, Straight TM, Holodniy M. Thrombocytopenia from combination treatment with oseltamivir and probenecid: case report, MedWatch data summary, and review of the literature. Pharmacotherapy 2009. link 39 Larsen OH, Ingerslev J, Sørensen B. Whole blood laboratory model of thrombocytopenia for use in evaluation of hemostatic interventions. Annals of hematology 2007. link 40 Tang J, Stern-Nezer S, Liu PC, Matyakhina L, Riordan M, Luban NL et al.. Mutation in the leucine-rich repeat C-flanking region of platelet glycoprotein Ib beta impairs assembly of von Willebrand factor receptor. Thrombosis and haemostasis 2004. link 41 Moeller KE, Touma SC. Prolonged thrombocytopenia associated with isotretinoin. The Annals of pharmacotherapy 2003. link 42 Jim RT. Transportational thrombocytopenia. Hawaii medical journal 2002. link 43 Thompson AA, Woodruff K, Feig SA, Nguyen LT, Schanen NC. Congenital thrombocytopenia and radio-ulnar synostosis: a new familial syndrome. British journal of haematology 2001. link 44 Gill JE, Davis KA, Cowart WJ, Nepacena FU, Kim YR. A rapid and accurate closed-tube immunoassay for platelets on an automated hematology analyzer. American journal of clinical pathology 2000. link 45 Azuno Y, Yaga K, Sasayama T, Kimoto K. Thrombocytopenia induced by Jui, a traditional Chinese herbal medicine. Lancet (London, England) 1999. link01336-7) 46 Bajaj R, Jain M, Kasat L, Naregal A, Borwankar SS. Tar syndrome with unilateral absent radius and associated esophageal atresia: a variant?. Indian journal of pediatrics 1999. link 47 Kroll H, Kiefel V, Santoso S. Clinical aspects and typing of platelet alloantigens. Vox sanguinis 1998. link 48 O'Grady P, Carney PA. Recurrent life-threatening thrombocytopenia in a patient with chronic "Parstelin" dependence. Irish medical journal 1997. link 49 Gonzalez J, Schwartz J, Gerstein G, Klainer AS, Bisaccia E. Case report: post-transfusion purpura. New Jersey medicine : the journal of the Medical Society of New Jersey 1996. link 50 Pedersen-Bjergaard U, Andersen M, Hansen PB. Thrombocytopenia induced by noncytotoxic drugs in Denmark 1968-91. Journal of internal medicine 1996. link 51 Pavithran K, Vijayalekshmi N. Thrombocytopenic purpura with tuberculous adenitis. Indian journal of medical sciences 1993. link 52 Najean Y, Lecompte T. Genetic thrombocytopenia with autosomal dominant transmission: a review of 54 cases. British journal of haematology 1990. link 53 Prasad R, Mukerji PK. Ethambutol-induced thrombocytopaenia. Tubercle 1989. link90053-6) 54 Dornic DI. Ocular hemorrhages in thrombocytopenia. American journal of optometry and physiological optics 1988. link 55 Cornbleet PJ, Kessinger S. Accuracy of low platelet counts on the Coulter S-Plus IV. American journal of clinical pathology 1985. link 56 Andrew M, Kelton J. Neonatal thrombocytopenia. Clinics in perinatology 1984. link 57 Naparstek Y, Abrahamov A, Cohen T, Brautbar C. Familial hereditary thrombocytopenia and HLA. American journal of hematology 1984. link 58 Lightsey AL. Thrombocytopenia in children. Pediatric clinics of North America 1980. link33852-4) 59 Khaleeli M, Giorgio AJ. Thrombocytopenia in heroin addicts: case reports. The International journal of the addictions 1980. link 60 Kim YD. Immunochemical characteristics of human anti-T antibodies. Vox sanguinis 1980. link 61 Berkessy S. Light microscopic characteristics of megathrombocytes in platelet spreading preparations. Annals of clinical research 1975. link 62 Amemiya H, Yokoyama T, Putnam CW, Torisu M, Starzl TE. The nature of antiplatelet activity in antilymphoblast ALG--with special reference to cross-reacting antibody, immunochemical characterization, and Coombs' positive thrombocytopenia in ALG-treated renal recipients. Clinical and experimental immunology 1972. link

    Original source

    1. [1]
      The clinical use of platelet transfusions: A systematic literature review and meta-analysis on behalf of the International Collaboration for Transfusion Medicine Guidelines. — Jug R, La Rocca U, Al-Riyami AZ, Bathla A, Metcalf RA, White SK et al. Transfusion (2025)
    2. [2]
      Platelet Transfusion: 2025 AABB and ICTMG International Clinical Practice Guidelines. — Metcalf RA, Nahirniak S, Guyatt G, Bathla A, White SK, Al-Riyami AZ et al. JAMA (2025)
    3. [3]
      A novel MECOM gene variant causes severe thrombocytopenia in a neonate: a case report and review of the literature. — Li J, Peng T, Cheng G, Yang L, Zhou J, Zhang R et al. Journal of medical case reports (2025)
    4. [4]
      Relationship between thromboembolic events and thrombopoietin receptor agonists: a pharmacovigilance analysis of the FDA Adverse Event Reporting System and the Japanese Adverse Drug Event Report. — Huang X, Liao X, Huang Y, Zhang C, Wang Z, Yu L BMJ open (2025)
    5. [5]
      National recommendations of the Croatian Chamber of Medical Biochemists and Working group for Laboratory hematology of the Croatian Society of Medical Biochemistry and Laboratory Medicine: Management of samples with suspected EDTA-induced pseudothrombocytopenia. — Milevoj Kopčinović L, Juričić G, Antončić D, Smaić F, Šimac B, Lapić I et al. Biochemia medica (2024)
    6. [6]
      Performance evaluation of a novel platelet count parameter, hybrid platelet count, on the BC-780 automated hematology analyzer. — Prompetchara E, Parnsamut C, Chirapanuruk A, Ketloy C Clinical chemistry and laboratory medicine (2024)
    7. [7]
      Thromboembolism adverse event profiles of thrombopoietin receptor agonists: a real-world, pharmacovigilance study. — Xu X, Zhang L, Zhang X, Huang W, Xie L, Ouyang M Expert opinion on drug safety (2024)
    8. [8]
      An Updated Comprehensive Pharmacovigilance Study of Drug-Induced Thrombocytopenia Based on FDA Adverse Event Reporting System Data. — Kunyu L, Shuping S, Chang S, Yiyue C, Qinyu X, Ting Z et al. Journal of clinical pharmacology (2024)
    9. [9]
      A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for avatrombopag. — Xue Z, Chen M, Wang M, Zhang F, Chen Z Scientific reports (2024)
    10. [10]
      Data mining and safety analysis of avatrombopag: a retrospective pharmacovigilance study based on the US food and drug administration's adverse event reporting system. — Zhu H, Wu M Scientific reports (2024)
    11. [11]
      Risk factors for thrombocytopenia in patients receiving linezolid therapy: a systematic review and meta-analysis. — Zhang D, Xu Y, Wang X, Hou L, Xing M, Xu S et al. European journal of clinical pharmacology (2023)
    12. [12]
      Thrombocytopenia Caused by Iron Infusion in a Patient with End-Stage Kidney Disease. — Bibi S, Naveed K, Haq A Journal of the College of Physicians and Surgeons--Pakistan : JCPSP (2023)
    13. [13]
      Performance of the Sysmex XN-V hematology analyzer in determining the immature platelet fraction in dogs: A preliminary study and reference values. — Jornet-Rius O, Mesalles-Naranjo M, Pastor J Veterinary clinical pathology (2023)
    14. [14]
      Outcomes of Patients with Thrombocytopenia Evaluated at Hematology Subspecialty Clinics. — Abdel Rahman ZH, Miller KC, Jabbour H, Alkhatib Y, Donthireddy V Hematology/oncology and stem cell therapy (2023)
    15. [15]
      Thrombocytopenia after Ad.26.COV2.S COVID-19 vaccine: Reports to the vaccine adverse event reporting system. — Woo EJ, Dimova RB Vaccine (2022)
    16. [16]
      Development of gates to measure the immature platelet fraction in C57BL/6J mice using the Sysmex XN-V series multispecies hematology analyzer. — Davenport P, Lorenz V, Liu ZJ, Feldman HA, Canas J, Nolton E et al. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc (2021)
    17. [17]
      Thrombocytopenia including immune thrombocytopenia after receipt of mRNA COVID-19 vaccines reported to the Vaccine Adverse Event Reporting System (VAERS). — Welsh KJ, Baumblatt J, Chege W, Goud R, Nair N Vaccine (2021)
    18. [18]
      Evaluation of the Expression Profile of Antibiotic-Induced Thrombocytopenia Using the Japanese Adverse Drug Event Report Database. — Asai Y, Yamamoto T, Abe Y International journal of toxicology (2021)
    19. [19]
      Blood collection, platelet isolation and measurement of platelet count and size in mice-a practical guide. — Aurbach K, Spindler M, Haining EJ, Bender M, Pleines I Platelets (2019)
    20. [20]
      Equine platelet concentrate preparation and validation. — Bozorgmanesh R, Magdesian KG, Sutton-Burges JW, Owens SD, Tablin F Journal of veterinary internal medicine (2019)
    21. [21]
      Comparative evaluation of platelet counts in two hematology analyzers and potential effects on prophylactic platelet transfusion decisions. — Hummel K, Sachse M, Hoffmann JJML, van Dun LPJM Transfusion (2018)
    22. [22]
      Isolated thrombocytopenia in childhood: what if it is not immune thrombocytopenia? — Lee AC Singapore medical journal (2018)
    23. [23]
      Research Progress of Platelet Transfusion in China. — Wang Q, Yang J, Stevens L, Wang D Transfusion medicine reviews (2017)
    24. [24]
      Ceftazidime-induced thrombocytopenia. — Domingo-Chiva E, Díaz-Rangel M, Monsalve-Naharro JÁ, Cuesta-Montero P, Catalá-Ripoll JV, García-Martínez EM Revista espanola de anestesiologia y reanimacion (2017)
    25. [25]
      Current Status of Platelet Transfusion in Pediatric Patients. — Sloan SR, Parker RI Transfusion medicine reviews (2016)
    26. [26]
      Haemostasis and safety measures before lumbar puncture in the haematology ward: the Danish routines. — Møller A, Bjerrum OW, Afshari A Acta haematologica (2015)
    27. [27]
      Guidance on platelet transfusion for patients with hypoproliferative thrombocytopenia. — Nahirniak S, Slichter SJ, Tanael S, Rebulla P, Pavenski K, Vassallo R et al. Transfusion medicine reviews (2015)
    28. [28]
      Recombinant human thrombopoietin alleviates infection-associated thrombocytopenia: a retrospective study in senile patients. — Lin J, Zhu H, Li S, Fan H, Lu X Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2015)
    29. [29]
      Platelet transfusion in hematology, oncology and surgery. — Wandt H, Schäfer-Eckart K, Greinacher A Deutsches Arzteblatt international (2014)
    30. [30]
      Protamine-induced thrombocytopenia? — Cuker A, Cines DB Blood (2013)
    31. [31]
      How low can you go? — Mitchell WB, Bussel JB Blood (2013)
    32. [32]
      How to approach thrombocytopenia. — Stasi R Hematology. American Society of Hematology. Education Program (2012)
    33. [33]
      Platelets in the neonatal period: developmental differences in platelet production, function, and hemostasis and the potential impact of therapies. — Sola-Visner M Hematology. American Society of Hematology. Education Program (2012)
    34. [34]
      Pseudotumerous enlargement of the umbilical cord owing to an intra-amniotic varicosity associated with thrombocytopenia. — Tröbs RB, Teig N, Neid M, Gernaianu G, Kozlowski P Journal of pediatric surgery (2012)
    35. [35]
      Thrombocytopenia after vaccination: case reports to the US Vaccine Adverse Event Reporting System, 1990-2008. — Woo EJ, Wise RP, Menschik D, Shadomy SV, Iskander J, Beeler J et al. Vaccine (2011)
    36. [36]
      Thrombocytopenia in pregnancy. — McCrae KR Hematology. American Society of Hematology. Education Program (2010)
    37. [37]
      Congenital amegakaryocytic thrombocytopenia and thrombocytopenia with absent radii. — Geddis AE Hematology/oncology clinics of North America (2009)
    38. [38]
      Thrombocytopenia from combination treatment with oseltamivir and probenecid: case report, MedWatch data summary, and review of the literature. — Raisch DW, Straight TM, Holodniy M Pharmacotherapy (2009)
    39. [39]
      Whole blood laboratory model of thrombocytopenia for use in evaluation of hemostatic interventions. — Larsen OH, Ingerslev J, Sørensen B Annals of hematology (2007)
    40. [40]
      Mutation in the leucine-rich repeat C-flanking region of platelet glycoprotein Ib beta impairs assembly of von Willebrand factor receptor. — Tang J, Stern-Nezer S, Liu PC, Matyakhina L, Riordan M, Luban NL et al. Thrombosis and haemostasis (2004)
    41. [41]
      Prolonged thrombocytopenia associated with isotretinoin. — Moeller KE, Touma SC The Annals of pharmacotherapy (2003)
    42. [42]
      Transportational thrombocytopenia. — Jim RT Hawaii medical journal (2002)
    43. [43]
      Congenital thrombocytopenia and radio-ulnar synostosis: a new familial syndrome. — Thompson AA, Woodruff K, Feig SA, Nguyen LT, Schanen NC British journal of haematology (2001)
    44. [44]
      A rapid and accurate closed-tube immunoassay for platelets on an automated hematology analyzer. — Gill JE, Davis KA, Cowart WJ, Nepacena FU, Kim YR American journal of clinical pathology (2000)
    45. [45]
      Thrombocytopenia induced by Jui, a traditional Chinese herbal medicine. — Azuno Y, Yaga K, Sasayama T, Kimoto K Lancet (London, England) (1999)
    46. [46]
      Tar syndrome with unilateral absent radius and associated esophageal atresia: a variant? — Bajaj R, Jain M, Kasat L, Naregal A, Borwankar SS Indian journal of pediatrics (1999)
    47. [47]
      Clinical aspects and typing of platelet alloantigens. — Kroll H, Kiefel V, Santoso S Vox sanguinis (1998)
    48. [48]
      Recurrent life-threatening thrombocytopenia in a patient with chronic "Parstelin" dependence. — O'Grady P, Carney PA Irish medical journal (1997)
    49. [49]
      Case report: post-transfusion purpura. — Gonzalez J, Schwartz J, Gerstein G, Klainer AS, Bisaccia E New Jersey medicine : the journal of the Medical Society of New Jersey (1996)
    50. [50]
      Thrombocytopenia induced by noncytotoxic drugs in Denmark 1968-91. — Pedersen-Bjergaard U, Andersen M, Hansen PB Journal of internal medicine (1996)
    51. [51]
      Thrombocytopenic purpura with tuberculous adenitis. — Pavithran K, Vijayalekshmi N Indian journal of medical sciences (1993)
    52. [52]
      Genetic thrombocytopenia with autosomal dominant transmission: a review of 54 cases. — Najean Y, Lecompte T British journal of haematology (1990)
    53. [53]
      Ethambutol-induced thrombocytopaenia. — Prasad R, Mukerji PK Tubercle (1989)
    54. [54]
      Ocular hemorrhages in thrombocytopenia. — Dornic DI American journal of optometry and physiological optics (1988)
    55. [55]
      Accuracy of low platelet counts on the Coulter S-Plus IV. — Cornbleet PJ, Kessinger S American journal of clinical pathology (1985)
    56. [56]
      Neonatal thrombocytopenia. — Andrew M, Kelton J Clinics in perinatology (1984)
    57. [57]
      Familial hereditary thrombocytopenia and HLA. — Naparstek Y, Abrahamov A, Cohen T, Brautbar C American journal of hematology (1984)
    58. [58]
      Thrombocytopenia in children. — Lightsey AL Pediatric clinics of North America (1980)
    59. [59]
      Thrombocytopenia in heroin addicts: case reports. — Khaleeli M, Giorgio AJ The International journal of the addictions (1980)
    60. [60]
      Immunochemical characteristics of human anti-T antibodies. — Kim YD Vox sanguinis (1980)
    61. [61]
      Light microscopic characteristics of megathrombocytes in platelet spreading preparations. — Berkessy S Annals of clinical research (1975)
    62. [62]
      The nature of antiplatelet activity in antilymphoblast ALG--with special reference to cross-reacting antibody, immunochemical characterization, and Coombs' positive thrombocytopenia in ALG-treated renal recipients. — Amemiya H, Yokoyama T, Putnam CW, Torisu M, Starzl TE Clinical and experimental immunology (1972)
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