Overview
Herpes zoster scleritis is a rare inflammatory condition affecting the sclera, often associated with varicella-zoster virus reactivation, leading to ocular complications including inflammation and potential vascular occlusions 1.Diagnosis
Clinical presentation includes ocular pain, redness, and visual disturbances 1.
Fundus fluorescein angiography may reveal vascular abnormalities, such as choroidal occlusions 1.
Histopathological examination can confirm the presence of viral inclusions and inflammatory changes 1.Management
Corticosteroids are often used to reduce inflammation; specific dosing varies but typically involves high-dose topical or systemic administration 1.
Antiviral therapy, such as acyclovir, is recommended to manage the underlying viral infection 1.
Adjunctive immunosuppressive agents like methotrexate or mycophenolate mofetil may be necessary in refractory cases 1.Special Populations
No specific data provided for pregnancy, pediatrics, or elderly populations in the given abstracts 1.
Patients with comorbidities like chronic sclerokeratouveitis may require tailored management approaches 1.Key Recommendations
Perform fundus fluorescein angiography to evaluate for choroidal vascular complications in suspected cases (Evidence: Weak) 1.
Initiate high-dose corticosteroid therapy alongside antiviral treatment for managing inflammation and viral activity (Evidence: Weak) 1.
Consider immunosuppressive agents for patients who do not respond to initial corticosteroid and antiviral therapy (Evidence: Weak) 1.References
1 Mourya D, Balamurugan S, Khanal R. A RARE COMPLICATION OF POSTERIOR SUBTENON INJECTION. Retinal cases & brief reports 2017. link