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Infectious Disease3228 papers

Oncovirus infection

Last edited: 4/23/2026

Overview

Oncovirus infections refer to viral infections that can impact patients undergoing oncology treatment, potentially complicating their care and outcomes. These infections can arise from various viral pathogens and may affect different organ systems, necessitating vigilant monitoring and management.

Diagnosis

  • Clinical symptoms and signs indicative of viral infection (e.g., fever, rash, respiratory symptoms) 629
  • Laboratory tests: Viral PCR, serology, and blood cultures to identify specific pathogens 529
  • Imaging studies: Chest X-ray, CT scans for localized infections or complications 633
  • Monitoring for organ dysfunction using scoring models (e.g., SOFA score) 30
  • Management

  • Antiviral therapy: Initiate based on identified virus (e.g., oseltamivir for influenza, acyclovir for herpes simplex) 629
  • Supportive care: Fluid management, antipyretics, and respiratory support as needed 633
  • Antibiotic prophylaxis: Consider in high-risk patients to prevent secondary bacterial infections 2033
  • Close monitoring for complications: Such as sepsis, thrombosis, and organ failure 630
  • Special Populations

  • Pediatrics: Increased vigilance for bone and joint infections; tailored diagnostic approaches 75
  • Elderly: Higher risk of severe infections; consider vitamin D status and supplementation to support immune function 39
  • Comorbidities: Patients with pre-existing conditions may require adjusted antiviral dosing and closer monitoring for adverse events 56
  • Key Recommendations

  • Implement routine viral screening in oncology patients presenting with unexplained fever or systemic symptoms to early identify oncovirus infections (Evidence: Moderate) 629
  • Utilize scoring systems (e.g., SOFA) to monitor for organ dysfunction in infected patients, facilitating timely intervention (Evidence: Moderate) 30
  • Consider vitamin D supplementation in elderly oncology patients to potentially reduce infection risk and severity (Evidence: Weak) 39
  • Enhance infection control practices, including hand hygiene and proper catheter care, to prevent secondary infections (Evidence: Expert opinion) 2033
  • References

    Showing 100 most recent of 387 indexed papers.

    1 Silva DR, Medeiros MAA, Rodrigues ARS, Rêgo VGS, Anjos RM, Oliveira Filho AA. Antibacterial potential of Citrus sinensis essential oil against foodborne pathogens: a systematic review. Brazilian journal of biology = Revista brasleira de biologia 2026. link 2 Zayed S. The Power of "I Don't Know". Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2026. link 3 Mokoala KMG, Kaoma C, Jibril F, Kabunda J, Sathekge M. Imaging of infection in Nephro-urology: A practical nuclear medicine-focused review. Seminars in nuclear medicine 2026. link 4 Sanchez KK, McCarville JL, Stengel SJ, Snyder JM, Williams AE, Ayres JS. Disease tolerance and infection pathogenesis age-related tradeoffs in mice. Nature 2026. link 5 Shearsmith L, Danson S, Gelcich S, Gibson A, Gordon K, Collinson F et al.. Electronic patient-reported adverse event monitoring in academic early-phase clinical trials: A feasibility study. Clinical trials (London, England) 2026. link 6 Zhao LX, Wang C, Zou J, Ranasinghe P. Machine Learning Model for Predicting Severe Adverse Events in Oncology Patients Using the US Food and Drug Administration Adverse Event Reporting System. JCO clinical cancer informatics 2026. link 7 Frey C, Elmi P. A pharmacovigilance analysis of carbapenem-related utilizing the FDA adverse event reporting system (FAERS) database from 2013 to 2025. The Journal of antimicrobial chemotherapy 2026. link 8 Zhou J, Wang D, Yan B. Infection at the vascular front: A delicate balance between defense and pathology. Microbial pathogenesis 2026. link 9 Parashar A, Mehta V, Sharma V, Thakur M. Gastrointestinal perforation in general oncology, metastatic colorectal cancer, and metastatic melanoma population. Medical oncology (Northwood, London, England) 2025. link 10 Kirkik D, Demircioglu S, Taş SK. TLR2 variants and . Upsala journal of medical sciences 2025. link 11 Fidelis J, Bernardo YAA, de Souza HCA, Conte-Junior CA, Paschoalin VMF. Modulating bacterial virulence: The role of food-plant essential oils in counteracting foodborne pathogen threats - A systematic review. International journal of food microbiology 2025. link 12 Ratti M. Reactivating experience: reintegrating retired oncologists into the healthcare system. The point of view of a young oncologist. Recenti progressi in medicina 2025. link 13 Lasch F, Carvalho JRB, Pothet C. Demonstration of Major Therapeutic Advantage From a Review of EU Conditional Marketing Authorizations in Oncology and Hematology. Clinical pharmacology and therapeutics 2025. link 14 Dizman N, Bakouny Z, Haykal T, Riano I, Desai A, Butt A et al.. Guide to Understanding and Supporting International Medical Graduates in Hematology/Oncology by the ASCO International Medical Graduates Community of Practice. JCO oncology practice 2025. link 15 Ren L, Li Y, Yin J, Sun X, Zheng J, Zheng Y et al.. Transient . Frontiers in bioscience (Landmark edition) 2025. link 16 Guo J, Tang Y, Yue Q, Yu H. A real-world pharmacovigilance study of FDA adverse event reporting system events for cefazolin. Medicine 2025. link 17 Hu S, Yu H, Liu Z. Analysis of infection-related adverse events induced by proton pump inhibitors based on the FAERS and JADER databases. Medicine 2025. link 18 Jiang C, Qian J, Lu Y, Zheng J. Exploration of adverse event profiles for cefotaxime: a disproportionality analysis using the FDA adverse event reporting system. BMC pharmacology & toxicology 2025. link 19 Xie L, Liu GW, Liu YN, Li PY, Hu XN, He XY et al.. Prevalence of . World journal of gastroenterology 2024. link 20 Dobrescu A, Constantin AM, Pinte L, Chapman A, Ratajczak P, Klerings I et al.. Effectiveness and Safety of Measures to Prevent Infections and Other Complications Associated With Peripheral Intravenous Catheters: A Systematic Review and Meta-analysis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024. link 21 Najem S, Mrabti H, Errihani H. Tackling Predatory Journals in Oncology: Training Is Key!. JCO global oncology 2024. link 22 Watson JL. Ruthlessly Subtract to Build Oncology Programs and Add Value. Clinical journal of oncology nursing 2024. link 23 . Volodymyr Oleksiyovych SHLYAKHOVENKO. Experimental oncology 2024. link 24 Sanford NN, Gyawali B. Financial Conflicts of Interest: Payment at the Expense of Patients?. JCO oncology practice 2024. link 25 Preti B, Lakkunarajah S, Sanatani M. The oncology ribbon of reflection: a novel tool to encourage trainee self-reflection. Canadian medical education journal 2024. link 26 Gasperoni L, Masini C, Toscano G, Cafaro A, Zani C, Andrianò C et al.. Pharmacy Workload in Clinical Trial Management: A Preliminary Complexity Assessment Tool for Sponsored Oncology and Haematology Trials. Current oncology (Toronto, Ont.) 2024. link 27 Simbu S, Orchard A, Vuuren SV. Essential Oil Compounds in Combination with Conventional Antibiotics for Dermatology. Molecules (Basel, Switzerland) 2024. link 28 Barnes LEA, White KA, Young MR, Ramsey PS, Cochran RL, Perkins KM. Physician perceptions of barriers to infection prevention and control in labor and delivery. Infection control and hospital epidemiology 2024. link 29 Kumar A, Dutt M, Dehury B, Martinez GS, Singh KP, Kelvin DJ. Formulation of next-generation polyvalent vaccine candidates against three important poxviruses by targeting DNA-dependent RNA polymerase using an integrated immunoinformatics and molecular modeling approach. Journal of infection and public health 2024. link 30 Li S, Tan T, Li J, Li H, Zhou L, Bai K et al.. Validating the performance of organ dysfunction scores in children with infection: A cohort study. PloS one 2024. link 31 Hansen CH. Evidence of immune imprinting or the effect of selection bias?. Science advances 2023. link 32 Jordán de Luna C, Fernández E, Mesía R, Clopés A. Clinical practice guidelines for the optimization of hemato-oncological care: the ICOPraxis. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023. link 33 Raimbault SC, Domenech C, Fuhrmann C, Bertrand A. Central-line-associated bloodstream infections in a pediatric oncology and hematology hospital at home program. Infection control and hospital epidemiology 2023. link 34 Burrell SA, Ross JG, Byrne C, Heverly M. The Effects of a Simulation-Based Experience with Standardized Participants on Learning and Clinical Decision-Making Related to Nursing Management of Oncologic Emergencies. Journal of cancer education : the official journal of the American Association for Cancer Education 2023. link 35 Norling B, Jung JH, Hwang EC, Han MA, Khaleel S, Schünemann HJ et al.. GRADE Reporting in Systematic Reviews Published in the Urological Literature (2009-2021). The Journal of urology 2023. link 36 Plitman E, Kim E, Patel R, Kohout S, Jin R, Chan V et al.. Development of an Automated and Scalable Virtual Assistant to Aid in PPE Adherence: A Study with Implications for Applications within Anesthesiology. Journal of medical systems 2023. link 37 Togami K, Yoshimatsu R, Yamanishi T, Maeda H, Izumi T, Miyatake K et al.. Removal of central venous port-catheter by the combination of interventional radiological procedures. Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy 2023. link 38 Gottlieb C, Henrich M, Liu PT, Yacoubian V, Wang J, Chun R et al.. (no title). Nutrients 2023. link 39 Pham H, Waterhouse M, Baxter C, Romero BD, McLeod DS, Armstrong BK et al.. Vitamin D supplementation and hospitalization for infection in older adults: A post-hoc analysis of data from the Australian D-Health Trial. The American journal of clinical nutrition 2023. link 40 Maher JM, Mendes RE, Huynh HK, Porsch EA, St Geme Iii JW, Yagupsky P et al.. In vitro Activity of Ceftaroline Against an International Collection of Kingella kingae Isolates Recovered From Carriers and Invasive Infections. The Pediatric infectious disease journal 2023. link 41 Chabner BA, Bates SE. Supreme Court and the Practice of Oncology. The oncologist 2022. link 42 Janjan N. Academic Promotion and Oncology Drug Development: Role, Responsibilities, and Integrity. Oncology (Williston Park, N.Y.) 2022. link 43 Samaha R, Kattan C, Rassy E, Kattan J. Learning by Debate: Innovative Tool in the Hematology-Oncology Fellowship Program. Journal of cancer education : the official journal of the American Association for Cancer Education 2022. link 44 De Corte T, Van Hoecke S, De Waele J. Artificial Intelligence in Infection Management in the ICU. Critical care (London, England) 2022. link 45 Stecca CE, Alt M, Jiang DM, Michelis G, Fallah-Rad N, Gill S et al.. Impact of the COVID-19 Pandemic on the Wellbeing of International Oncology and Hematology Fellows at the Princess Margaret Cancer Center (PMCC). Seminars in oncology 2022. link 46 Sundberg E, Hoffman T, Nilsson A, Pahnke S, Enblad G, Kolstad L et al.. COVID-19 seroprevalence and clinical picture in Swedish pediatric oncology and hematology patients. Pediatric blood & cancer 2022. link 47 Makhoul I, Anders M, Siegel R, Chiang A, Markham MJ, Chen RC et al.. Hematology/Oncology Fellowship Programs' Participation in the Quality Oncology Practice Initiative. JCO oncology practice 2022. link 48 Julián-Jiménez A, González Del Castillo J, García-Lamberechts EJ, Huarte Sanz I, Navarro Bustos C, Rubio Díaz R et al.. A bacteraemia risk prediction model: development and validation in an emergency medicine population. Infection 2022. link 49 Udalova V, Bhatia V, Polyakova M. Association of Family Income With Morbidity and Mortality Among US Lower-Income Children and Adolescents. JAMA 2022. link 50 Psihogios A, Madampage C, Faught BE. Contemporary nutrition-based interventions to reduce risk of infection among elderly long-term care residents: A scoping review. PloS one 2022. link 51 Heo JY, Cho MK, Kim S. Data mining for detecting signals of adverse drug reaction of doxycycline using the Korea adverse event reporting system database. The Journal of dermatological treatment 2022. link 52 Coppry M, Duret S, Berdaï D, Miremont-Salamé G, Fourrier-Réglat A, Haramburu F et al.. Adverse drug reactions induced by cotrimoxazole: Still a lot of preventable harm. Fundamental & clinical pharmacology 2022. link 53 Morris SE, Tarquini SJ, Yusufov M, Adolf E, Amonoo HL, Bain PA et al.. Burnout in psychosocial oncology clinicians: A systematic review. Palliative & supportive care 2021. link 54 Badon HR, Pearlman RL, Brodell RT. Foot rash and joint pain. The Journal of family practice 2021. link 55 Schouw HM, Huisman LA, Janssen YF, Slart RHJA, Borra RJH, Willemsen ATM et al.. Targeted optical fluorescence imaging: a meta-narrative review and future perspectives. European journal of nuclear medicine and molecular imaging 2021. link 56 Lapière J, Christen C, Kerouani-Lafaye G, Monard A, Turcry F, Grude F et al.. Evaluation of Clinical Trials in Onco-haematology: A New Method Based on Risk Analysis and Multidisciplinarity. Therapeutic innovation & regulatory science 2021. link 57 Aboubakr M, Abdelkader A, Habotta OA, Adel N, Emam MA, Abdelhiee EY et al.. Cefepime and diclofenac sodium combined treatment-potentiated multiple organ injury: Role of oxidative damage and disrupted lipid metabolism. Journal of biochemical and molecular toxicology 2021. link 58 Adawee M, Cole S. Establishing an evidence-based infection surveillance program for home care and hospice: A large Midwest health system's experience. American journal of infection control 2021. link 59 Correia Pinheiro L, Giezen TJ, Wolff-Holz E, Weise M, Laslop A, Hidalgo-Simon A. Identifiability of Biologicals: An Analysis Using EudraVigilance, the European Union's Database of Reports of Suspected Adverse Drug Reactions. Clinical pharmacology and therapeutics 2021. link 60 Bengoechea JA. Viruses to fight other viruses: the influenza vaccine case. EMBO molecular medicine 2020. link 61 Vergani S, Yuan J. B-1 Cells Carry the Memory of Neonatal Immune Imprinting. Immunity 2020. link 62 Sarier M, Ceyhan AM, Sepin N, Ozel E, Inal MM, Kukul E et al.. HPV infection in urology practice. 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Journal of the American Medical Directors Association 2020. link 67 Kurtaran B, Kuscu F, Korkmaz P, Ozdemir B, Inan D, Oztoprak N et al.. A snapshot of geriatric infections in Turkey: ratio of geriatric inpatients in hospitals and evaluation of their infectious diseases: A multicenter point prevalence study. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2020. link 68 McFatrich M, Brondon J, Lucas NR, Hinds PS, Maurer SH, Mack JW et al.. Mapping child and adolescent self-reported symptom data to clinician-reported adverse event grading to improve pediatric oncology care and research. Cancer 2020. link 69 Lim TR, Rangaswami AA, Dubin AM, Kapphahn KI, Sakarovitch C, Long J et al.. QTc Prolongation and Risk of Torsades de Pointes in Hospitalized Pediatric Oncology Patients. The Journal of pediatrics 2020. link 70 Andrés C, Andaluz-Ojeda D, Cicuendez R, Nogales L, Martín S, Martin-Fernandez M et al.. MR- proADM to detect specific types of organ failure in infection. European journal of clinical investigation 2020. link 71 Duff P. Prevention of Infection After Cesarean Delivery. Clinical obstetrics and gynecology 2019. link 72 Flores EJ, Mull NK, Lavenberg JG, Mitchell MD, Leas BF, Williams A et al.. Using a 10-step framework to support the implementation of an evidence-based clinical pathways programme. BMJ quality & safety 2019. link 73 Iskrov G, Greenberg D, Yakimov I, Cholakova H, Stefanov R. What Is the Value of Innovative Pharmaceutical Therapies in Oncology and Hematology? A Willingness-to-Pay Study in Bulgaria. Value in health regional issues 2019. link 74 Zhou J, Vallejo J, Kluetz P, Pazdur R, Kim T, Keegan P et al.. Overview of Oncology and Hematology Drug Approvals at US Food and Drug Administration Between 2008 and 2016. Journal of the National Cancer Institute 2019. link 75 Akinkugbe O, Stewart C, McKenna C. 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    Original source

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