Management
This study demonstrates that the incorporation of BMP-2 within a PLGA/MBG scaffold, enhanced by ZIF-8 nanoparticles, significantly improves osteogenic activity and mechanical properties, suggesting a promising approach for bone regeneration in clinical settings [PMID:37701821].
The controlled and sustained release of BMP-2 facilitated by the scaffold material described in this study could minimize complications associated with traditional BMP-2 delivery methods, such as burst release and ectopic bone formation [PMID:37701821].
In the study by Satoh et al. [PMID:7480226], noncoronal approaches were preferred for males and young females, while coronal approaches, often combined with forehead lifting and canthopexy, were indicated for females over 40 years old to achieve optimal facial balance and rejuvenation.
Satoh et al. [PMID:7480226] noted that associated surgeries were performed concurrently in some cases to enhance facial aesthetics and balance beyond just the reduction of the zygomatic prominence.
Special Populations
The authors [PMID:7480226] emphasize the importance of considering patient wishes and cultural background when selecting operative procedures for zygomatic reduction in Oriental patients, particularly Japanese females.
References
1 Ma R, Su Y, Cao R, Wang K, Yang P. Enhanced Osteogenic Activity and Bone Repair Ability of PLGA/MBG Scaffolds Doped with ZIF-8 Nanoparticles Loaded with BMP-2. International journal of nanomedicine 2023. link 2 Satoh K, Ohkubo F, Tsukagoshi T. Consideration of operative procedures for zygomatic reduction in Orientals: based on a consecutive series of 28 clinical cases. Plastic and reconstructive surgery 1995. link