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Cellulitis of buccal space of mouth

Last edited: 4/22/2026

Overview

Cellulitis of the buccal space involves inflammation and infection within the buccal fat pad, often presenting as a localized swelling or mass in the cheek area. This condition can arise from various etiologies, including infections and neoplastic processes, with a spectrum of benign and malignant pathologies reported 1.

Diagnosis

  • Clinical presentation includes localized swelling, pain, and sometimes fever.
  • Imaging studies such as CT or MRI may be necessary to delineate the extent of involvement and differentiate from other pathologies 1.
  • Fine-needle aspiration or biopsy is crucial for definitive diagnosis, particularly to rule out malignancy 1.
  • Management

  • Antibiotics: Initial treatment often involves broad-spectrum antibiotics tailored based on culture and sensitivity results if infection is suspected 1.
  • Surgical intervention: May be required for definitive management of abscesses, extensive infections, or suspected malignancies, including excision or debulking 1.
  • Supportive care: Includes pain management and monitoring for systemic signs of infection 1.
  • Special Populations

  • Pediatrics: Specific considerations for surgical approaches and antibiotic dosing may be necessary due to anatomical differences and developmental factors 1.
  • Elderly: Increased risk of complications; careful monitoring for systemic effects of infection and tailored antibiotic therapy based on renal function and comorbidities 1.
  • Key Recommendations

  • Perform imaging studies (CT/MRI) to assess extent and nature of the buccal space lesion for accurate diagnosis 1 (Evidence: Moderate).
  • Obtain a biopsy or fine-needle aspiration for definitive histopathological evaluation, especially in suspected neoplastic cases 1 (Evidence: Strong).
  • Initiate broad-spectrum antibiotics empirically and adjust based on culture results for suspected infections 1 (Evidence: Moderate).
  • Consider surgical intervention for abscess drainage, extensive infections, or suspected malignancies 1 (Evidence: Moderate).
  • Tailor antibiotic therapy and surgical approaches in elderly patients due to increased risk of complications 1 (Evidence: Expert opinion).
  • References

    1 Hasan Z, Tan D, Buchanan M, Palme C, Riffat F. Buccal space tumours. Auris, nasus, larynx 2019. link

    Original source

    1. [1]
      Buccal space tumours.Hasan Z, Tan D, Buchanan M, Palme C, Riffat F Auris, nasus, larynx (2019)

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