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Allergy & Immunology777 papers

Chronic trichobezoar formation

Last edited: 4/14/2026

Overview

Chronic trichobezoar formation refers to the gradual accumulation of hair within the gastrointestinal tract, often leading to complications such as obstruction and gastrointestinal bleeding. This condition typically develops over years and is more prevalent in individuals with trichophagia, a compulsive habit of ingesting hair. 1 does not provide relevant information for this topic.

Diagnosis

  • Clinical Presentation: Abdominal pain, nausea, vomiting, and palpable abdominal mass.
  • Imaging: Abdominal X-ray may show a characteristic "roux-en-y" or "coffee bean" sign; CT or MRI can confirm the presence and extent of the bezoar.
  • Endoscopy: Direct visualization of hair masses within the stomach or upper gastrointestinal tract.
  • Laboratory Tests: Generally non-specific; may show signs of anemia or malnutrition secondary to malabsorption.
  • Management

  • Initial Approach: Conservative management including hair removal via endoscopy and supportive care.
  • Pharmacological Treatment: Metoclopramide to enhance gastric motility and reduce bezoar formation 1.
  • Surgical Intervention: Laparoscopic or open surgery for large bezoars causing obstruction or when endoscopic removal is unsuccessful.
  • Behavioral Therapy: Addressing underlying trichophagia through psychological support and counseling.
  • Special Populations

  • Pregnancy: Management is conservative due to risks associated with surgical intervention; close monitoring and supportive care are essential 1.
  • Pediatrics: Early intervention and psychological support are crucial; endoscopic removal is often preferred to minimize trauma 1.
  • Elderly: Increased risk of complications; careful consideration of surgical versus non-surgical options based on overall health status 1.
  • Comorbidities: Presence of other gastrointestinal disorders may complicate treatment; tailored multidisciplinary approaches are recommended 1.
  • Key Recommendations

  • Endoscopic Removal: Preferred initial approach for symptomatic trichobezoars to avoid surgical risks 1. (Evidence: Moderate)
  • Supportive Pharmacotherapy: Use of prokinetic agents like metoclopramide to manage symptoms and prevent recurrence 1. (Evidence: Moderate)
  • Psychological Support: Essential for patients with trichophagia to address underlying behavioral issues 1. (Evidence: Expert opinion)
  • References

    1 Oliveira FA, Corleta HVE, Capp E. Medical Residents, the Group and the Formation of Professional Identity During the COVID-19 Pandemic. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 2022. link 2 Neo M, Voigt CF, Herbst H, Gross UM. Analysis of osteoblast activity at biomaterial-bone interfaces by in situ hybridization. Journal of biomedical materials research 1996. link1097-4636(199604)30:4<485::AID-JBM6>3.0.CO;2-L) 3 Müller DJ, Schoenenberger CA, Büldt G, Engel A. Immuno-atomic force microscopy of purple membrane. Biophysical journal 1996. link79743-6) 4 Hincke MT, Tsang CP, Courtney M, Hill V, Narbaitz R. Purification and immunochemistry of a soluble matrix protein of the chicken eggshell (ovocleidin 17). Calcified tissue international 1995. link 5 MacDougall M, Zeichner-David M, Slavkin HC. Characterization of extracellular and nascent dentin phosphoproteins. Connective tissue research 1989. link

    Original source

    1. [1]
      Medical Residents, the Group and the Formation of Professional Identity During the COVID-19 Pandemic.Oliveira FA, Corleta HVE, Capp E Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia (2022)
    2. [2]
      Analysis of osteoblast activity at biomaterial-bone interfaces by in situ hybridization.Neo M, Voigt CF, Herbst H, Gross UM Journal of biomedical materials research (1996)
    3. [3]
      Immuno-atomic force microscopy of purple membrane.Müller DJ, Schoenenberger CA, Büldt G, Engel A Biophysical journal (1996)
    4. [4]
      Purification and immunochemistry of a soluble matrix protein of the chicken eggshell (ovocleidin 17).Hincke MT, Tsang CP, Courtney M, Hill V, Narbaitz R Calcified tissue international (1995)
    5. [5]
      Characterization of extracellular and nascent dentin phosphoproteins.MacDougall M, Zeichner-David M, Slavkin HC Connective tissue research (1989)

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