Overview
Transfusion-transmitted infections (TTIs) are a significant concern, particularly in regions with a reliance on replacement blood donors 1. HIV is one such infection that can be transmitted through blood transfusions 1.Diagnosis
Management
Enhanced donor screening is needed to address the burden of HIV among blood donors 1.Special Populations
Key Recommendations
Implement enhanced donor screening to reduce the prevalence of transfusion-transmitted HIV 1. (Evidence: Moderate)
Recognize that replacement blood donors have a higher HIV prevalence (0.26%) compared to voluntary blood donors (0.13%) 1. (Evidence: Moderate)
Be aware of regional variations in HIV seroprevalence among blood donors, with India showing the highest prevalence (0.19%) and Bangladesh and Bhutan the lowest (0.02%) in South Asia 1. (Evidence: Moderate)References
1 Raquib A, Salman A, Ziaulhaq A, Al-Mamun F, Shaikh Y, Raquib R et al.. Geospatial Distribution of HIV Seroprevalence Among Blood Donors in South Asian Countries: A Systematic Review and Meta-Analysis. AIDS and behavior 2025. link