Overview
Chlamydia trachomatis* is a bacterial sexually transmitted infection (STI) that has increased in the United States 1.
Few chemoprophylaxis options exist for bacterial STIs, including chlamydia 1.Diagnosis
No specific diagnostic criteria or grading are mentioned in the provided abstracts.Management
Doxycycline postexposure prophylaxis (doxy PEP) is recommended for bacterial STI prevention 1.
The recommended dose for doxy PEP is 200 mg, not to exceed 200 mg every 24 hours 1.
Doxy PEP should be self-administered within 72 hours after oral, vaginal, or anal sex 1.
Doxy PEP should be implemented within a comprehensive sexual health approach, including risk reduction counseling and STI screening 1.Special Populations
No specific information is provided for pregnancy, pediatrics, elderly, or comorbidities.Key Recommendations
For gay, bisexual, and other men who have sex with men (MSM) and transgender women (TGW) diagnosed with a bacterial STI in the past 12 months, counseling regarding the use of doxycycline postexposure prophylaxis (doxy PEP) to prevent bacterial STIs should be provided 1. (Evidence: Strong)
Providers should offer MSM and TGW who have had a bacterial STI diagnosed in the past 12 months a prescription for doxy PEP to be self-administered within 72 hours after sex, following shared decision-making 1. (Evidence: Strong)
The recommended dose of doxy PEP is 200 mg, not to exceed 200 mg every 24 hours 1. (Evidence: Strong)References
1 Bachmann LH, Barbee LA, Chan P, Reno H, Workowski KA, Hoover K et al.. CDC Clinical Guidelines on the Use of Doxycycline Postexposure Prophylaxis for Bacterial Sexually Transmitted Infection Prevention, United States, 2024. MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports 2024. link