Diagnosis
125I-labelled polymeric micelles demonstrated higher bone uptake and reduced liver or spleen uptake compared to stannous colloid, indicating enhanced targetability for bone imaging [PMID:11771706].
Management
The 125I-labelling efficiency of the micelles was above 90% and remained stable in human serum for 24 hours, supporting their feasibility in clinical settings [PMID:11771706].
Prognosis & Follow-up
With higher blood maintenance and specific bone uptake, these micelles could offer improved longitudinal assessment in the follow-up of bone diseases [PMID:11771706].
References
1 Park YJ, Lee JY, Chang YS, Jeong JM, Chung JK, Lee MC et al.. Radioisotope carrying polyethylene oxide-polycaprolactone copolymer micelles for targetable bone imaging. Biomaterials 2002. link00196-x)
1 papers cited of 4 indexed.