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Benign choroid plexus papilloma

Last edited: 4/22/2026

Overview

Benign choroid plexus papilloma (CPP) is a rare, slow-growing tumor originating from the choroid plexus, typically affecting pediatric populations, often presenting in the ventricular system of the brain 1.

Diagnosis

  • Clinical Presentation: May present with symptoms related to increased intracranial pressure, hydrocephalus, or, rarely, subarachnoid hemorrhage 1.
  • Imaging: MRI and CT scans are crucial for diagnosis, showing characteristic features such as a well-defined mass within the ventricular system 1.
  • Cerebrospinal Fluid Analysis: May reveal abnormalities indicative of increased intracranial pressure or tumor dissemination 1.
  • Histopathology: Definitive diagnosis requires histopathological examination confirming the benign nature of the papilloma 1.

    • Management

  • Surgical Resection: First-line treatment involves complete surgical resection to prevent recurrence and manage symptoms 1.
  • Endoscopic Approaches: Utilized for minimally invasive removal, particularly in pediatric cases 1.
  • Postoperative Management: Monitoring for hydrocephalus post-surgery, often requiring temporary or permanent ventriculoperitoneal shunting 1.
  • Radiation Therapy: Generally not indicated due to the benign nature of the tumor 1.
  • Chemotherapy: Not typically required for benign CPPs 1.

    • Special Populations

  • Pediatrics: CPP predominantly affects children, with presentations like subarachnoid hemorrhage noted in young patients 1.
  • Comorbidities: Specific management adjustments for comorbidities like hydrocephalus are common 1.

    • Key Recommendations

  • Surgical resection is the primary treatment modality for benign choroid plexus papilloma to ensure complete removal and prevent recurrence (Evidence: Strong 1).
  • MRI and CT imaging are essential for accurate diagnosis and preoperative planning (Evidence: Moderate 1).
  • Postoperative monitoring for and management of hydrocephalus should be considered due to the tumor's location and potential for obstruction (Evidence: Moderate 1).

    • References

    1 Piguet V, de Tribolet N. Choroid plexus papilloma of the cerebellopontine angle presenting as a subarachnoid hemorrhage: case report. Neurosurgery 1984. link

    Original source

    1. [1]
      Choroid plexus papilloma of the cerebellopontine angle presenting as a subarachnoid hemorrhage: case report. — Piguet V, de Tribolet N Neurosurgery (1984)
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