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Cardiology21 papers

Gastric dilatation-volvulus-torsion syndrome

Last edited: 4/15/2026

Overview

Gastric dilatation-volvulus-torsion (GDV) syndrome is a life-threatening condition primarily affecting large and giant breed dogs, characterized by the acute distension of the stomach and its subsequent twisting, leading to severe systemic complications including shock and multiple organ dysfunction 1.

Diagnosis

  • Clinical signs: Distended abdomen, retching without vomiting, tachycardia, weakness, and collapse 1.
  • Diagnostic imaging: Radiography often shows a "double bubble" sign or absent pylorus; abdominal ultrasound can confirm gastric distension and torsion 1.
  • Laboratory tests: Elevated lactate levels, electrolyte imbalances, and evidence of disseminated intravascular coagulation (DIC) 1.
  • Management

  • Emergency surgical intervention: Immediate gastropexy to secure the stomach and correct torsion 1.
  • Fluid resuscitation: Aggressive intravenous fluid therapy to manage shock, typically crystalloids (e.g., lactated Ringer's) 1.
  • Anticoagulation management: Monitoring and management of DIC, possibly including fresh frozen plasma (FFP) for coagulation support 1.
  • Antiarrhythmic therapy: For managing cardiac arrhythmias, consider beta-blockers or antiarrhythmic drugs as needed 1.
  • Antimicrobial prophylaxis: Broad-spectrum antibiotics to prevent or treat aspiration pneumonia and secondary infections 1.
  • Post-operative care: Close monitoring for gastrointestinal complications such as ileus and delayed gastric emptying 1.
  • Special Populations

  • No specific data provided: The abstracts do not cover special populations such as pregnancy, pediatrics, elderly, or comorbidities 1.
  • Key Recommendations

  • Immediate surgical intervention for confirmed GDV to correct torsion and perform gastropexy to prevent recurrence (Evidence: Strong 1).
  • Aggressive fluid resuscitation with crystalloids to manage shock and support hemodynamic stability (Evidence: Strong 1).
  • Monitor and manage disseminated intravascular coagulation (DIC) with appropriate coagulation support, including fresh frozen plasma if necessary (Evidence: Moderate 1).
  • References

    1 Sharp CR, Rozanski EA. Cardiovascular and systemic effects of gastric dilatation and volvulus in dogs. Topics in companion animal medicine 2014. link

    Original source

    1. [1]
      Cardiovascular and systemic effects of gastric dilatation and volvulus in dogs.Sharp CR, Rozanski EA Topics in companion animal medicine (2014)

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