Overview
Chronic pulmonary aspergillosis (CPA) is a progressive fungal disease that can develop in patients with underlying lung conditions 1. It frequently occurs in survivors of pulmonary tuberculosis (TB), contributing to post-TB lung disease 1.Diagnosis
Diagnosis of CPA in TB survivors is based on clinical symptoms, radiographic abnormalities, and microbiological evidence 1.
Prevalence of CPA among patients with TB varies: 9% during treatment and 13% posttreatment 1.
Among patients with persistent respiratory symptoms after TB treatment, CPA prevalence is significantly higher, reaching 48% 1.Management
No specific management strategies are detailed in the provided abstracts.Special Populations
No specific information on special populations is covered in the provided abstracts.Key Recommendations
Consider CPA in patients with persistent respiratory symptoms following pulmonary tuberculosis treatment 1. (Evidence: Moderate)
Recognize that CPA prevalence is higher in patients with persistent respiratory symptoms after TB treatment (up to 48%) compared to the general TB population (9-13%) 1. (Evidence: Moderate)References
1 Madden AE, Ofori SK, Budu M, Sisay E, Dooley B, Murray MB. A Systematic Review of Chronic Pulmonary Aspergillosis Among Patients Treated for Pulmonary Tuberculosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2025. link