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Invasive aural aspergillosis

Last edited: 4/10/2026

Overview

Invasive aural aspergillosis is a serious fungal infection affecting the ear canal and potentially deeper structures. It is particularly concerning in immunocompromised individuals, such as those with hematologic malignancies or who have undergone hematopoietic stem cell transplantation.

Diagnosis

  • Diagnosis involves clinical suspicion and confirmation through imaging and/or histopathology.
  • ECIL-6 guidelines provide recommendations for diagnostic strategies in at-risk populations 1.
  • Management

  • ECIL-6 guidelines offer recommendations for targeted therapy of invasive aspergillosis 1.
  • Specific treatment regimens are detailed within the ECIL-6 update 1.
  • Key Recommendations

  • ECIL-6 guidelines provide recommendations for the targeted treatment of invasive aspergillosis 1. (Evidence: Expert opinion)
  • The ECIL-6 update includes recommendations for diagnostic strategies for invasive fungal infections 1. (Evidence: Expert opinion)
  • The ECIL-6 guidelines are updated every two years, with the latest presented being the 2015 update 1. (Evidence: Expert opinion)
  • References

    1 Tissot F, Agrawal S, Pagano L, Petrikkos G, Groll AH, Skiada A et al.. ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients. Haematologica 2017. link

    Original source

    1. [1]

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