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Adenoviral nervous system infection

Last edited: 4/10/2026

Overview

Adenoviral nervous system infections are a subset of neuroinfectious emergencies that can lead to rapid functional decline 1. Prompt identification and management are crucial to prevent permanent deficits or death 1.

Diagnosis

  • Neurologic infections become emergencies when they lead to a rapid decline in a patient's function 1.
  • Emergent complications include cerebral edema and herniation, spinal cord compression, hydrocephalus, vasculopathy resulting in ischemic stroke, venous thrombosis, intracerebral hemorrhage, status epilepticus, and neuromuscular respiratory weakness 1.
  • Advanced MRI techniques can be used to evaluate nervous system infections 1.

    • Management

  • New research on the use of dexamethasone in viral and fungal infections is reviewed 1.

    • Key Recommendations

  • Neurologic infections become emergencies when they lead to a rapid decline in a patient's function 1. (Evidence: Expert opinion)
  • Emergent complications from neurologic infections, if not identified promptly, can lead to permanent deficits or death 1. (Evidence: Expert opinion)
  • Advanced MRI techniques can be used to evaluate nervous system infections 1. (Evidence: Expert opinion)

    • References

    1 Reynolds AS. Neuroinfectious Emergencies. Continuum (Minneapolis, Minn.) 2024. link

    Original source

    1. [1]
      Neuroinfectious Emergencies. — Reynolds AS Continuum (Minneapolis, Minn.) (2024)
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