Overview
Manganism is a neurological disorder resulting from chronic occupational manganese exposure, characterized by Parkinsonian-like symptoms and cognitive impairment 1. Cognitive deficits associated with manganese exposure can affect various domains, including processing speed, attention, and memory 1.Diagnosis
Cognitive deficits in processing speed, attention, working memory, reaction time, cognitive control, and visual attention have been observed in workers exposed to manganese 1.
Regression analysis suggests a potential exposure-effect relationship between manganese exposure and cognitive functioning 1.Management
No specific management strategies for dementia caused by manganese were detailed in the provided abstract.Special Populations
The provided abstract focuses on cognitive performance in working adults exposed to manganese 1.Key Recommendations
Occupational manganese exposure is associated with significant cognitive impairments in workers, including reduced performance in processing speed, attention, working memory, reaction time, cognitive control, and visual attention 1. (Evidence: Moderate)
There is an indication of an exposure-effect relationship between manganese exposure and cognitive functioning in exposed workers 1. (Evidence: Moderate)References
1 Vlasak T, Dujlovic T, Barth A. Manganese exposure and cognitive performance: A meta-analytical approach. Environmental pollution (Barking, Essex : 1987) 2023. link