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Cardiology49 papers

Microscopic enteritis

Last edited: 4/22/2026

Overview

Microscopic enteritis refers to inflammation of the small intestine that is often subclinical but can manifest with symptoms like diarrhea, malabsorption, and abdominal pain, frequently seen in patients with prior radiation exposure 1.

Diagnosis

  • Endoscopic findings showing mucosal changes
  • Histopathological evidence of inflammation on biopsy samples
  • Symptom correlation with radiation exposure history
  • Stool analysis for malabsorption markers (e.g., fat content) 1

    • Management

  • First-line treatments:
    • - Nonsteroidal anti-inflammatory drugs (NSAIDs) like acetylsalicylic acid (ASA) at standard doses for symptom relief and healing of epithelial ulceration 1
  • Adjunctive treatments:
    • - Dietary modifications to reduce irritants and enhance nutrient absorption - Symptomatic management with antidiarrheals as needed 1

    Special Populations

  • Radiation history: Management strategies are particularly relevant for patients with a history of abdominal or pelvic radiation therapy 1
  • Other populations: Limited data; recommendations vary based on radiation exposure context 1

    • Key Recommendations

  • Consider acetylsalicylic acid therapy for patients with complications of radiation enteritis to promote healing and symptom relief (Evidence: Moderate) 1
  • Implement dietary modifications alongside pharmacological treatments to support nutritional status and reduce symptoms (Evidence: Expert opinion) 1
  • Regular monitoring through endoscopic and histopathological assessments is crucial for evaluating treatment efficacy in microscopic enteritis (Evidence: Expert opinion) 1

    • References

    1 Ludgate CM. Preliminary report: acetylsalicylic acid therapy in the treatment of complications following abdominal radiation. Journal of the Canadian Association of Radiologists 1985. link

    Original source

    1. [1]
      Preliminary report: acetylsalicylic acid therapy in the treatment of complications following abdominal radiation. — Ludgate CM Journal of the Canadian Association of Radiologists (1985)
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