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Glaucomatous atrophy of optic disc

Last edited: 4/10/2026

Overview

Glaucomatous optic disc atrophy is characterized by damage to the optic nerve head, typically associated with elevated intraocular pressure. This condition leads to progressive visual field loss and can result in irreversible blindness if left untreated.

Diagnosis

  • Diagnosis involves a comprehensive eye examination including visual acuity, intraocular pressure measurement, gonioscopy, visual field testing, and optic disc evaluation 1.
  • Optic disc evaluation focuses on identifying characteristic glaucomatous changes such as increased cup-to-disc ratio, thinning of the neuroretinal rim, and nerve fiber layer defects 1.
  • Advanced glaucoma is defined by significant visual field loss or optic disc damage that places the patient at high risk of further vision loss 1.
  • Management

  • Treatment aims to lower intraocular pressure to prevent or slow disease progression 1.
  • First-line treatment typically involves topical ocular hypotensive medications 1.
  • Adjunctive treatments may include laser therapy or incisional surgery if medical management is insufficient 1.
  • Key Recommendations

  • A comprehensive eye examination is recommended for the detection, evaluation, and monitoring of adult patients with advanced glaucoma 1. (Evidence: Expert opinion)
  • Treatment strategies for advanced glaucoma should focus on lowering intraocular pressure to prevent further optic nerve damage and visual field loss 1. (Evidence: Expert opinion)
  • Regular follow-up and monitoring are essential for patients with advanced glaucoma to assess treatment efficacy and disease progression 1. (Evidence: Expert opinion)
  • References

    1 Díez-Álvarez L, Beltrán-Agullo L, Loscos J, Pazos M, Ponte-Zúñiga B, Pinazo-Durán MD et al.. Advanced glaucoma. Clinical practice guideline. Archivos de la Sociedad Espanola de Oftalmologia 2023. link

    Original source

    1. [1]
      Advanced glaucoma. Clinical practice guideline.Díez-Álvarez L, Beltrán-Agullo L, Loscos J, Pazos M, Ponte-Zúñiga B, Pinazo-Durán MD et al. Archivos de la Sociedad Espanola de Oftalmologia (2023)

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