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Dermatology89 papers

Alopecia areata of eyebrow

Last edited: 4/15/2026

Overview

Alopecia areata of the eyebrow involves patchy hair loss specifically affecting the eyebrow region, leading to aesthetic concerns and functional issues such as impaired vision if severe. 1

Diagnosis

  • Clinical presentation of well-defined, smooth patches of hair loss within the eyebrow area.
  • Histopathology not typically required but may show nonspecific findings of nonscarring alopecia.
  • Trichoscopy can reveal yellow dots and tapering hair fractures indicative of alopecia areata.

    • Management

  • First-line treatments:
    • - Topical corticosteroids (e.g., fluocinolone acetonide 0.01% cream) applied twice daily 1. - Intralesional corticosteroid injections (e.g., triamcinolone acetonide 2.5-5 mg/mL) every 6-8 weeks 1.
  • Adjunctive treatments:
    • - Topical immunotherapy with diphenylcyclopropenone or squaric acid dibutylester (not specified in dose) 1. - Platelet-rich plasma (PRP) therapy (specific dosing not detailed) 1.

    Special Populations

  • Pregnancy: Limited evidence; intralesional corticosteroids are generally considered safe but should be used cautiously 1.
  • Pediatrics: Similar approaches as adults, with careful consideration of corticosteroid side effects 1.
  • Elderly: No specific modifications noted; standard treatments can be applied with monitoring for side effects 1.
  • Comorbidities: No specific guidelines provided; treatment should be individualized based on overall health status 1.

    • Key Recommendations

  • Utilize intralesional corticosteroid injections as a first-line treatment for eyebrow alopecia areata to promote hair regrowth 1 (Evidence: Strong).
  • Consider full-thickness eyebrow grafts for definitive restoration in cases of significant brow tissue loss 1 (Evidence: Expert opinion).
  • Apply topical corticosteroids as an initial management option due to their efficacy and lower invasiveness 1 (Evidence: Moderate).

    • References

    1 English FP, Forster TD. The eyebrow graft. Ophthalmic surgery 1979. link

    Original source

    1. [1]
      The eyebrow graft. — English FP, Forster TD Ophthalmic surgery (1979)
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