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Endocrinology5 papers

Abscess of adrenal gland

Last edited: 4/15/2026

Overview

Adrenal abscess is a rare but serious infection involving the adrenal gland, often presenting as a localized mass with potential for systemic complications due to its proximity to major vascular structures 2.

Diagnosis

  • Imaging: Computed tomography (CT) is crucial for diagnosis, revealing an adrenal mass with possible extension into adjacent structures like the renal hilum and inferior vena cava 2.
  • Aspiration and Drainage: Needle aspiration can confirm diagnosis via identification of purulent material 1.
  • Pathology: Histopathologic examination confirms the presence of abscess with purulent debris 2.
  • Management

  • Percutaneous Drainage: First-line treatment for nonsurgical management, particularly in neonates 1.
  • Antibiotics: Broad-spectrum antibiotics are typically initiated empirically, tailored based on culture and sensitivity results (specific drug classes/doses not detailed in abstracts).
  • Supportive Care: Includes management of systemic symptoms and monitoring for complications such as sepsis 12.
  • Special Populations

  • Neonates: Nonsurgical approaches like percutaneous drainage are feasible and effective 1.
  • Key Recommendations

  • Utilize CT imaging for definitive diagnosis and assessment of extension (Evidence: Moderate 2).
  • Consider percutaneous drainage as a primary treatment modality, especially in neonates (Evidence: Weak 1).
  • Initiate broad-spectrum antibiotics and tailor based on culture results (Evidence: Expert opinion).
  • References

    1 Mondor C, Gauthier M, Garel L, Filiatrault D, Grignon A. Nonsurgical management of neonatal adrenal abscess. Journal of pediatric surgery 1988. link80026-5) 2 O'Brien WM, Choyke PL, Copeland J, Klappenbach RS, Lynch JH. Computed tomography of adrenal abscess. Journal of computer assisted tomography 1987. link

    Original source

    1. [1]
      Nonsurgical management of neonatal adrenal abscess.Mondor C, Gauthier M, Garel L, Filiatrault D, Grignon A Journal of pediatric surgery (1988)
    2. [2]
      Computed tomography of adrenal abscess.O'Brien WM, Choyke PL, Copeland J, Klappenbach RS, Lynch JH Journal of computer assisted tomography (1987)

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