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Pediatrics3 papers

Erythema multiforme minor

Last edited: 4/15/2026

Overview

Erythema multiforme minor is a self-limiting, acute, immune-mediated mucocutaneous reaction characterized by target-like lesions and often triggered by herpes simplex virus infection 1.

Diagnosis

  • Clinical presentation includes targetoid erythematous lesions, often on the face and extremities 1.
  • Typically diagnosed clinically based on morphology and distribution of lesions 1.
  • No specific laboratory tests are required, though herpes simplex virus (HSV) testing may be considered if infection is suspected 1.
  • Management

  • First-line treatment involves supportive care and symptom management 1.
  • Topical corticosteroids can be used for localized lesions to reduce inflammation 1.
  • Antiviral therapy, such as acyclovir, may be considered if HSV is implicated as the trigger 1.
  • Special Populations

  • No specific guidance provided for pregnancy, pediatrics, elderly, or comorbidities in the given abstracts 1.
  • Key Recommendations

  • Diagnose erythema multiforme minor clinically based on characteristic lesion morphology and distribution (Evidence: Expert opinion 1).
  • Initiate supportive care and consider topical corticosteroids for symptomatic relief (Evidence: Expert opinion 1).
  • Prescribe antiviral therapy like acyclovir if herpes simplex virus is suspected as the trigger (Evidence: Expert opinion 1).
  • References

    1 Touwen BC, Lok-Meijer TY, Huisjes HJ, Olinga AA. The recovery rate of neurologically deviant newborns. Early human development 1982. link90132-3)

    Original source

    1. [1]
      The recovery rate of neurologically deviant newborns.Touwen BC, Lok-Meijer TY, Huisjes HJ, Olinga AA Early human development (1982)

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