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Dermatology25 papers

Hidradenitis suppurativa of multiple sites

Last edited: 4/10/2026

Overview

Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by recurrent, painful nodules, abscesses, and sinus tracts, typically affecting apocrine gland-rich areas like the axillae, groin, and buttocks 1. Multiple treatment modalities are utilized, with varying degrees of effectiveness 1.

Diagnosis

  • Diagnosis is primarily clinical, based on the presence of characteristic lesions 1.
  • Grading systems, such as the Goodman Baron qualitative scar grading system, can be used to assess severity 1.
  • Management

  • Combined Therapies: Platelet-rich plasma (PRP) combined with laser therapy demonstrated the highest effectiveness in patient satisfaction scores and scar grading in a network meta-analysis 1.
  • Laser Therapy: Laser treatment alone was also found to be effective for acne scars 1.
  • Microneedling: Microneedling, with or without PRP, showed moderate effectiveness for acne scars 1.
  • Autologous Fat Grafting: Autologous fat grafting was found to be less effective compared to laser and combined PRP and laser therapies 1.
  • Platelet-Rich Plasma (PRP): PRP alone was the least effective monotherapy for acne scars in the analyzed studies 1.
  • Key Recommendations

  • Combined therapy of PRP and laser may be the most effective treatment for acne scars 1. (Evidence: Moderate)
  • Laser therapy alone is an effective treatment option for acne scars 1. (Evidence: Moderate)
  • Microneedling, with or without PRP, can be considered for the management of acne scars 1. (Evidence: Moderate)
  • References

    1 Jiang M, Liu T, Liu X, Liu L, Jiang X, Zhang Z et al.. A Network Meta-analysis to Explore the Effectiveness of the Different Treatment Modalities in Acne Scars. Aesthetic plastic surgery 2024. link

    Original source

    1. [1]
      A Network Meta-analysis to Explore the Effectiveness of the Different Treatment Modalities in Acne Scars.Jiang M, Liu T, Liu X, Liu L, Jiang X, Zhang Z et al. Aesthetic plastic surgery (2024)

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