← Back to guidelines
Otolaryngology (ENT)474 papers

Adenocarcinoma of maxillary sinus

Last edited: 4/15/2026

Overview

Adenocarcinoma of the maxillary sinus is a malignant neoplasm arising from the epithelial lining of the maxillary sinus, often presenting with symptoms such as nasal obstruction, epistaxis, and facial pain 1.

Diagnosis

  • Clinical Evaluation: Essential for initial assessment and symptom correlation 1.
  • Imaging: Conventional sinus radiographs are valuable, showing acceptable interobserver agreement for diagnosing maxillary sinus disease (kappa values 0.45-0.58) 2.
  • Specific Radiographic Findings: Look for complete opacity, fluid levels, and mucosal swelling; agreement on these findings ranges from fair to good 2.
  • Management

  • Surgical Intervention: Modified Caldwell-Luc procedure shows reduced post-operative sensitivity disorders (8.7% vs 33% with classical technique) 1.
  • Technique Modifications: Include specific mucoperiosteal incision types and strategic antrostomy site and size adjustments 1.
  • Special Populations

  • No Specific Guidance Provided: Abstracts do not cover unique considerations for pregnancy, pediatrics, elderly, or comorbidities 12.
  • Key Recommendations

  • Employ modified Caldwell-Luc surgical techniques to minimize post-operative sensitivity disorders in treating maxillary sinus disease (Evidence: Moderate) 1.
  • Utilize conventional sinus radiographs for diagnosis, acknowledging fair to good interobserver agreement among specialists (Evidence: Moderate) 2.
  • Consider specific radiographic findings like complete opacity and mucosal swelling for confirming maxillary sinus disease, despite variability in interpretation (Evidence: Moderate) 2.
  • References

    1 Ferekidis E, Tzounakos P, Kandiloros D, Kaberos A, Adamopoulos G. Modifications of the Caldwell-Luc procedure for the prevention of post-operative sensitivity disorders. The Journal of laryngology and otology 1996. link 2 Hartog B, Van Benthem PP, Van Waes PF, Ten Hove W, Hordijk GJ. Value of sinus radiographs in the diagnosis of maxillary sinus disease: interobserver agreement on sinus radiographs by otolaryngologists and radiologists. Clinical otolaryngology and allied sciences 1996. link

    Original source

    1. [1]
      Modifications of the Caldwell-Luc procedure for the prevention of post-operative sensitivity disorders.Ferekidis E, Tzounakos P, Kandiloros D, Kaberos A, Adamopoulos G The Journal of laryngology and otology (1996)
    2. [2]
      Value of sinus radiographs in the diagnosis of maxillary sinus disease: interobserver agreement on sinus radiographs by otolaryngologists and radiologists.Hartog B, Van Benthem PP, Van Waes PF, Ten Hove W, Hordijk GJ Clinical otolaryngology and allied sciences (1996)

    HemoChat

    by SPINAI

    Evidence-based clinical decision support powered by SNOMED-CT, Neo4j GraphRAG, and NASS/AO/NICE guidelines.

    ⚕ For clinical reference only. Not a substitute for professional judgment.

    © 2026 HemoChat. All rights reserved.
    Research·Pricing·Privacy & Terms·Refund·SNOMED-CT · NASS · AO Spine · NICE · GraphRAG