Overview
Autonomic disorders caused by marine toxins are rare conditions resulting from exposure to neurotoxic substances produced by marine organisms, affecting primarily the autonomic nervous system. These toxins can lead to a spectrum of symptoms including but not limited to gastrointestinal disturbances, cardiovascular irregularities, and altered sweating and temperature regulation 1.Diagnosis
Clinical presentation of autonomic dysfunction following marine exposure
Laboratory analysis for specific marine toxin levels in biological samples
Electrocardiogram (ECG) and autonomic function tests to assess cardiovascular and peripheral autonomic function 1Management
Supportive care including fluid and electrolyte balance management
Symptomatic treatment with anticholinergics or cholinergic agents depending on specific symptoms
Monitoring and management of cardiovascular complications with beta-blockers or other appropriate agents as needed 1Special Populations
No specific data provided regarding pregnancy, pediatrics, elderly, or comorbidities in the context of marine toxin-induced autonomic disorders 123Key Recommendations
Conduct thorough environmental exposure history to identify potential marine toxin exposure 1 (Evidence: Expert opinion)
Implement supportive care measures focusing on maintaining homeostasis and managing symptoms 1 (Evidence: Expert opinion)
Monitor cardiovascular status closely due to potential autonomic dysfunction impacts 1 (Evidence: Expert opinion)References
1 Paerl RW, Curtis NP, Bittner MJ, Cohn MR, Gifford SM, Bannon CC et al.. Use and detection of a vitamin B1 degradation product yields new views of the marine B1 cycle and plankton metabolite exchange. mBio 2023. link
2 Moore M, Walsh M, Bailey J, Brunson D, Gulland F, Landry S et al.. Sedation at sea of entangled North Atlantic right whales (Eubalaena glacialis) to enhance disentanglement. PloS one 2010. link
3 Wang J. Offshore safety case approach and formal safety assessment of ships. Journal of safety research 2002. link00005-1)