Perinatal anoxic-ischemic brain injury

Overview

Diagnosis

Management

References

Showing 100 most recent of 245 indexed papers.

1 Tsenov G, Bano I, Velíková M, Kútna V, Chodounská H, Kudová E et al.. Pregnanolone Glutamate: A Dual-Fate Delivery System for Neuroactive Steroids in Perinatal Focal Cerebral Ischemia. International journal of molecular sciences 2026. link 2 Liu Y, Gu Y, Jin F, Guo M, Tian Z, Li Y et al.. Intermittent Hypoxia Preconditioning Protects Against Ischemic Brain Injury in Mice via a PF4-Dependent Paracrine Mechanism. Stroke 2026. link 3 Van Roy S, Hsu L, Ho J, Scirica BM, Fischer D, Snider SB et al.. Quantitative and Radiological Assessment of Post-cardiac-Arrest Comatose Patients with Diffusion-Weighted Magnetic Resonance Imaging. Neurocritical care 2025. link 4 Sun Y, Shen B, Wang T, Zhang G, Wang P, Huang H et al.. Restorative effects and mechanisms of neural stem cell transplantation on ischemic brain injury based on the Wnt signaling pathway. The International journal of neuroscience 2025. link 5 Wang Y, Jia Z, Zheng M, Wang P, Gao J, Zhang X et al.. Inhibition of miR-142-3p promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury by targeting FoxM1. Molecular and cellular biochemistry 2025. link 6 Rees P, Gale C, Battersby C, Williams C, Purkayastha M, Zylbersztejn A et al.. Childhood Health and Educational outcomes afteR perinatal Brain injury (CHERuB): protocol for a population-matched cohort study. BMJ open 2024. link 7 Liu X, Jia X. Neuroprotection of Stem Cells Against Ischemic Brain Injury: From Bench to Clinic. Translational stroke research 2024. link 8 Liu X, Jia X. Stem Cell Therapy for Ischemic Brain Injury: Early Intranasal Delivery after Cardiac Arrest. Translational stroke research 2024. link 9 Imai K, Hara H, Sawada T, Wada M. Comparison of the Clinical Characteristics of Infants with Punctate White Matter Lesions and/or Cystic Lesions. Neuropediatrics 2023. link 10 Hashemi P, Nouri-Vaskeh M, Alizadeh L, Baghbanzadeh A, Badalzadeh R, Askari E et al.. NETosis in ischemic/reperfusion injuries: An organ-based review. Life sciences 2022. link 11 de Roux Q, Lidouren F, Kudela A, Slassi L, Kohlhauer M, Boissady E et al.. Argon Attenuates Multiorgan Failure in Relation with HMGB1 Inhibition. International journal of molecular sciences 2021. link 12 Lee JH, Bok JH, Park SB, Pagire HS, Na YJ, Rim E et al.. Optimization of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury. Bioorganic & medicinal chemistry letters 2020. link 13 Queme LF, Weyler AA, Cohen ER, Hudgins RC, Jankowski MP. A dual role for peripheral GDNF signaling in nociception and cardiovascular reflexes in the mouse. Proceedings of the National Academy of Sciences of the United States of America 2020. link 14 Burda R, Morochovič R, Némethová M, Burda J. Remote ischemic postconditioning as well as blood plasma from double-conditioned donor ameliorate reperfusion syndrome in skeletal muscle. Journal of plastic surgery and hand surgery 2020. link 15 Yu Y, Yan Y, Luo Z, Luo P, Xiao N, Sun X et al.. Effects of human umbilical cord blood CD34. Brain & development 2019. link 16 Bueno GGG, Barros MCM, Guinsburg R. Preterm infants with peri/intraventricular hemorrhage have poorer habituation responses to external stimuli. Jornal de pediatria 2019. link 17 Zuluaga M, Gueguen V, Letourneur D, Pavon-Djavid G. Astaxanthin-antioxidant impact on excessive Reactive Oxygen Species generation induced by ischemia and reperfusion injury. Chemico-biological interactions 2018. link 18 Lai JCY, Rocha-Ferreira E, Ek CJ, Wang X, Hagberg H, Mallard C. Immune responses in perinatal brain injury. Brain, behavior, and immunity 2017. link 19 Wen XR, Fu YY, Liu HZ, Wu J, Shao XP, Zhang XB et al.. Neuroprotection of Sevoflurane Against Ischemia/Reperfusion-Induced Brain Injury Through Inhibiting JNK3/Caspase-3 by Enhancing Akt Signaling Pathway. Molecular neurobiology 2016. link 20 Perrone S, Tataranno LM, Stazzoni G, Ramenghi L, Buonocore G. Brain susceptibility to oxidative stress in the perinatal period. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2015. link 21 Jantzie LL, Talos DM, Jackson MC, Park HK, Graham DA, Lechpammer M et al.. Developmental expression of N-methyl-D-aspartate (NMDA) receptor subunits in human white and gray matter: potential mechanism of increased vulnerability in the immature brain. Cerebral cortex (New York, N.Y. : 1991) 2015. link 22 Gomez-Rodriguez V, Orbe J, Martinez-Aguilar E, Rodriguez JA, Fernandez-Alonso L, Serneels J et al.. Functional MMP-10 is required for efficient tissue repair after experimental hind limb ischemia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015. link 23 Davidson JO, Green CR, Bennet L, Gunn AJ. Battle of the hemichannels--Connexins and Pannexins in ischemic brain injury. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2015. link 24 Uchiyama A, Yamada K, Perera B, Ogino S, Yokoyama Y, Takeuchi Y et al.. Protective effect of MFG-E8 after cutaneous ischemia-reperfusion injury. The Journal of investigative dermatology 2015. link 25 Shi R, Wang S, Qi X, Chen S, Chen P, Zhang Q. Lose dose genistein inhibits glucocorticoid receptor and ischemic brain injury in female rats. Neurochemistry international 2014. link 26 Tsuji T, Okumura A, Kidokoro H, Hayakawa F, Kubota T, Maruyama K et al.. Differences between periventricular hemorrhagic infarction and periventricular leukomalacia. Brain & development 2014. link 27 Sealock R, Zhang H, Lucitti JL, Moore SM, Faber JE. Congenic fine-mapping identifies a major causal locus for variation in the native collateral circulation and ischemic injury in brain and lower extremity. Circulation research 2014. link 28 Ramanantsoa N, Fleiss B, Bouslama M, Matrot B, Schwendimann L, Cohen-Salmon C et al.. Bench to cribside: the path for developing a neuroprotectant. Translational stroke research 2013. link 29 Malek M, Duszczyk M, Zyszkowski M, Ziembowicz A, Salinska E. Hyperbaric oxygen and hyperbaric air treatment result in comparable neuronal death reduction and improved behavioral outcome after transient forebrain ischemia in the gerbil. Experimental brain research 2013. link 30 Thaler NS, Reger SL, Ringdahl EN, Mayfield JW, Goldstein G, Allen DN. Neuropsychological profiles of six children with anoxic brain injury. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence 2013. link 31 Rosenkranz K, Tenbusch M, May C, Marcus K, Meier C. Changes in Interleukin-1 alpha serum levels after transplantation of umbilical cord blood cells in a model of perinatal hypoxic-ischemic brain damage. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2013. link 32 Domercq M, Mato S, Soria FN, Sánchez-gómez MV, Alberdi E, Matute C. Zn2+ -induced ERK activation mediates PARP-1-dependent ischemic-reoxygenation damage to oligodendrocytes. Glia 2013. link 33 Roze E, Harris PA, Ball G, Elorza LZ, Braga RM, Allsop JM et al.. Tractography of the corticospinal tracts in infants with focal perinatal injury: comparison with normal controls and to motor development. Neuroradiology 2012. link 34 Kielland A, Camassa LM, Døhlen G, Munthe LA, Blomhoff R, Amiry-Moghaddam M et al.. NF-κB activity in perinatal brain during infectious and hypoxic-ischemic insults revealed by a reporter mouse. Brain pathology (Zurich, Switzerland) 2012. link 35 Packard AE, Hedges JC, Bahjat FR, Stevens SL, Conlin MJ, Salazar AM et al.. Poly-IC preconditioning protects against cerebral and renal ischemia-reperfusion injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012. link 36 Hammers DW, Sarathy A, Pham CB, Drinnan CT, Farrar RP, Suggs LJ. Controlled release of IGF-I from a biodegradable matrix improves functional recovery of skeletal muscle from ischemia/reperfusion. Biotechnology and bioengineering 2012. link 37 Rosier-van Dunné FM, van Wezel-Meijler G, Kaschula RO, Wranz PA, Odendaal HJ, de Vries JI. Placental histology related to fetal brain sonography. Archives of disease in childhood. Fetal and neonatal edition 2011. link 38 Schmitz T, Felderhoff-Mueser U, Sifringer M, Groenendaal F, Kampmann S, Heep A. Expression of soluble Fas in the cerebrospinal fluid of preterm infants with posthemorrhagic hydrocephalus and cystic white matter damage. Journal of perinatal medicine 2011. link 39 Guan J. Insulin-like growth factor -1 (IGF-1) derived neuropeptides, a novel strategy for the development of pharmaceuticals for managing ischemic brain injury. CNS neuroscience & therapeutics 2011. link 40 Leipälä JA, Partanen E, Kushnerenko E, Huotilainen M, Fellman V. Perinatal cerebral insults alter auditory event-related potentials. Early human development 2011. link 41 Furukawa S, Sameshima H, Yang L, Ikenoue T. Acetylcholine receptor agonist reduces brain damage induced by hypoxia-ischemia in newborn rats. Reproductive sciences (Thousand Oaks, Calif.) 2011. link 42 Mohr C, Brady JD, Rossi DJ. Young age and low temperature, but not female gender delay ATP loss and glutamate release, and protect Purkinje cells during simulated ischemia in cerebellar slices. Neuropharmacology 2010. link 43 Yeh CH, Hsu SP, Yang CC, Chien CT, Wang NP. Hypoxic preconditioning reinforces HIF-alpha-dependent HSP70 signaling to reduce ischemic renal failure-induced renal tubular apoptosis and autophagy. Life sciences 2010. link 44 Markus T, Hansson SR, Cronberg T, Cilio C, Wieloch T, Ley D. β-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices. Journal of neuroinflammation 2010. link 45 Tooze JA, Gaussoin SA, Resnick SM, Fischbein NJ, Robinson JG, Bryan RN et al.. A uniform approach to modeling risk factor relationships for ischemic lesion prevalence and extent: the Women's Health Initiative Magnetic Resonance Imaging study. Neuroepidemiology 2010. link 46 Katayama T, Tanaka H, Yoshida T, Uehara T, Minami M. Neuronal injury induces cytokine-induced neutrophil chemoattractant-1 (CINC-1) production in astrocytes. Journal of pharmacological sciences 2009. link 47 Takashima S, Itoh M, Oka A. A history of our understanding of cerebral vascular development and pathogenesis of perinatal brain damage over the past 30 years. Seminars in pediatric neurology 2009. link 48 Chen W, Ostrowski RP, Obenaus A, Zhang JH. Prodeath or prosurvival: two facets of hypoxia inducible factor-1 in perinatal brain injury. Experimental neurology 2009. link 49 Pluta R, Ułamek M, Jabłoński M. Alzheimer's mechanisms in ischemic brain degeneration. Anatomical record (Hoboken, N.J. : 2007) 2009. link 50 Jin-qiao S, Bin S, Wen-hao Z, Yi Y. Basic fibroblast growth factor stimulates the proliferation and differentiation of neural stem cells in neonatal rats after ischemic brain injury. Brain & development 2009. link 51 Maitre NL, Marshall DD, Price WA, Slaughter JC, O'Shea TM, Maxfield C et al.. Neurodevelopmental outcome of infants with unilateral or bilateral periventricular hemorrhagic infarction. Pediatrics 2009. link 52 Goodman PG, Mehta AR, Castresana MR. Predicting ischemic brain injury after intraoperative cardiac arrest during cardiac surgery using the BIS monitor. Journal of clinical anesthesia 2009. link 53 Abdel-Rahman U, Risteski P, Klaeffling C, Mitrev Z, Ackermann H, Matheis G et al.. The influence of controlled limb reperfusion with PGE1 on reperfusion injury after prolonged ischemia. The Journal of surgical research 2009. link 54 Cullen NK, Crescini C, Bayley MT. Rehabilitation outcomes after anoxic brain injury: a case-controlled comparison with traumatic brain injury. PM & R : the journal of injury, function, and rehabilitation 2009. link 55 Zhao S, Chen N, Yang Z, Huang L, Zhu Y, Guan S et al.. Ischemia deteriorates the spike encoding of rat cerebellar Purkinje cells by raising intracellular Ca2+. Biochemical and biophysical research communications 2008. link 56 Voloboueva LA, Duan M, Ouyang Y, Emery JF, Stoy C, Giffard RG. Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008. link 57 Ozturk H, Ozturk H, Dokucu AI. The role of cell adhesion molecules in ischemic epididymal injury. International urology and nephrology 2008. link 58 Salter MG, Fern R. The mechanisms of acute ischemic injury in the cell processes of developing white matter astrocytes. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008. link 59 Kuchukhidze G, Unterberger I, Dobesberger J, Embacher N, Walser G, Haberlandt E et al.. Electroclinical and imaging findings in ulegyria and epilepsy: a study on 25 patients. Journal of neurology, neurosurgery, and psychiatry 2008. link 60 Geudens N, Wuyts WA, Rega FR, Vanaudenaerde BM, Neyrinck AP, Verleden GM et al.. N-acetyl cysteine attenuates the inflammatory response in warm ischemic pig lungs. The Journal of surgical research 2008. link 61 Lodygensky GA, Inder TE, Neil JJ. Application of magnetic resonance imaging in animal models of perinatal hypoxic-ischemic cerebral injury. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2008. link 62 Zhao P, Peng L, Li L, Xu X, Zuo Z. Isoflurane preconditioning improves long-term neurologic outcome after hypoxic-ischemic brain injury in neonatal rats. Anesthesiology 2007. link 63 Chung H, Kim E, Lee DH, Seo S, Ju S, Lee D et al.. Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation. Endocrinology 2007. link 64 Crawford RS, Hashmi FF, Jones JE, Albadawi H, McCormack M, Eberlin K et al.. A novel model of acute murine hindlimb ischemia. American journal of physiology. Heart and circulatory physiology 2007. link 65 Back SA, Craig A, Kayton RJ, Luo NL, Meshul CK, Allcock N et al.. Hypoxia-ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007. link 66 Kitano H, Kirsch JR, Hurn PD, Murphy SJ. Inhalational anesthetics as neuroprotectants or chemical preconditioning agents in ischemic brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007. link 67 Jensen FE. Developmental factors regulating susceptibility to perinatal brain injury and seizures. Current opinion in pediatrics 2006. link 68 Cuzzocrea S, Wang ZQ. Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion. Pharmacological research 2005. link 69 Plock JA, Contaldo C, Sakai H, Tsuchida E, Leunig M, Banic A et al.. Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?. American journal of physiology. Heart and circulatory physiology 2005. link 70 Sutton TA, Kelly KJ, Mang HE, Plotkin Z, Sandoval RM, Dagher PC. Minocycline reduces renal microvascular leakage in a rat model of ischemic renal injury. American journal of physiology. Renal physiology 2005. link 71 Rytter A, Cardoso CM, Johansson P, Cronberg T, Hansson MJ, Mattiasson G et al.. The temperature dependence and involvement of mitochondria permeability transition and caspase activation in damage to organotypic hippocampal slices following in vitro ischemia. Journal of neurochemistry 2005. link 72 Northington FJ, Graham EM, Martin LJ. Apoptosis in perinatal hypoxic-ischemic brain injury: how important is it and should it be inhibited?. Brain research. Brain research reviews 2005. link 73 Sfaello I, Baud O, Arzimanoglou A, Gressens P. Topiramate prevents excitotoxic damage in the newborn rodent brain. Neurobiology of disease 2005. link 74 Rutherford M, Counsell S, Allsop J, Boardman J, Kapellou O, Larkman D et al.. Diffusion-weighted magnetic resonance imaging in term perinatal brain injury: a comparison with site of lesion and time from birth. Pediatrics 2004. link 75 Neil JJ, Inder TE. Imaging perinatal brain injury in premature infants. Seminars in perinatology 2004. link 76 Pétrilli V, Herceg Z, Hassa PO, Patel NS, Di Paola R, Cortes U et al.. Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. The Journal of clinical investigation 2004. link 77 Yu L, Huang Z, Mariani J, Wang Y, Moskowitz M, Chen JF. Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury. Nature medicine 2004. link 78 Perlman JM. Brain injury in the term infant. Seminars in perinatology 2004. link 79 Back SA, Rivkees SA. Emerging concepts in periventricular white matter injury. Seminars in perinatology 2004. link 80 Alizadeh N, Pittet B, Tenorio X, Pyke C, Baetens D, Schlaudraff KU et al.. Active-site inactivated FVIIa decreases thrombosis and necrosis in a random skin flap model of acute ischemia. The Journal of surgical research 2004. link 81 Chan RK, Austen WG, Ibrahim S, Ding GY, Verna N, Hechtman HB et al.. Reperfusion injury to skeletal muscle affects primarily type II muscle fibers. The Journal of surgical research 2004. link 82 Jensen A, Garnier Y, Middelanis J, Berger R. Perinatal brain damage--from pathophysiology to prevention. European journal of obstetrics, gynecology, and reproductive biology 2003. link00175-1) 83 Golovneva ES, Popov GK. Expression of vascular endothelial growth factor during neoangiogenesis stimulated by exposure to high-intensity laser radiation. Bulletin of experimental biology and medicine 2003. link 84 Crepel V, Epsztein J, Ben-Ari Y. Ischemia induces short- and long-term remodeling of synaptic activity in the hippocampus. Journal of cellular and molecular medicine 2003. link 85 Merchant SH, Gurule DM, Larson RS. Amelioration of ischemia-reperfusion injury with cyclic peptide blockade of ICAM-1. American journal of physiology. Heart and circulatory physiology 2003. link 86 Prokai L, Prokai-Tatrai K, Perjesi P, Zharikova AD, Perez EJ, Liu R et al.. Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection. Proceedings of the National Academy of Sciences of the United States of America 2003. link 87 Yunoki M, Nishio S, Ukita N, Anzivino MJ, Lee KS. Characteristics of hypothermic preconditioning influencing the induction of delayed ischemic tolerance. Journal of neurosurgery 2002. link 88 Moore TM, Shirah WB, Khimenko PL, Paisley P, Lausch RN, Taylor AE. Involvement of CD40-CD40L signaling in postischemic lung injury. American journal of physiology. Lung cellular and molecular physiology 2002. link 89 Moriyama H, Noguchi T, Takeno S, Harada K, Kudo T, Uchida Y. Analysis of mucosal regeneration and the expression profile of heat shock protein 70 in the isolated small bowel segment. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2002. link 90 Berger R, Garnier Y, Jensen A. Perinatal brain damage: underlying mechanisms and neuroprotective strategies. Journal of the Society for Gynecologic Investigation 2002. link 91 Zhou T, Chen JL, Song W, Wang F, Zhang MJ, Ni PH et al.. Effect of N-desulfated heparin on hepatic/renal ischemia reperfusion injury in rats. World journal of gastroenterology 2002. link 92 Brana C, Benham C, Sundstrom L. A method for characterising cell death in vitro by combining propidium iodide staining with immunohistochemistry. Brain research. Brain research protocols 2002. link00201-5) 93 Michetti F, Gazzolo D. S100B protein in biological fluids: a tool for perinatal medicine. Clinical chemistry 2002. link 94 de Laveaucoupet J, Audibert F, Guis F, Rambaud C, Suarez B, Boithias-Guérot C et al.. Fetal magnetic resonance imaging (MRI) of ischemic brain injury. Prenatal diagnosis 2001. link 95 Wijdicks EF, Campeau NG, Miller GM. MR imaging in comatose survivors of cardiac resuscitation. AJNR. American journal of neuroradiology 2001. link 96 Lysiak JJ, Turner SD, Nguyen QA, Singbartl K, Ley K, Turner TT. Essential role of neutrophils in germ cell-specific apoptosis following ischemia/reperfusion injury of the mouse testis. Biology of reproduction 2001. link 97 Mori K, Itoh Y, Saito J, Takeyama Y, Kurata Y, Kaneko M et al.. Post-resuscitative hypothermic bypass reduces ischemic brain injury in swine. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2001. link 98 Sato W, Kadomatsu K, Yuzawa Y, Muramatsu H, Hotta N, Matsuo S et al.. Midkine is involved in neutrophil infiltration into the tubulointerstitium in ischemic renal injury. Journal of immunology (Baltimore, Md. : 1950) 2001. link 99 Seo SY, Yun BS, Ryoo IJ, Choi JS, Joo CK, Chang SY et al.. Complestatin is a noncompetitive peptide antagonist of N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors: secure blockade of ischemic neuronal death. The Journal of pharmacology and experimental therapeutics 2001. link 100 Chui H. Vascular dementia, a new beginning: shifting focus from clinical phenotype to ischemic brain injury. Neurologic clinics 2000. link70234-6)