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Cardiology2284 papers

Chronic heart disease

Last edited: 4/17/2026

Overview

Chronic heart disease encompasses a range of conditions affecting the heart's structure and function, leading to impaired cardiac performance and increased morbidity and mortality. Effective management focuses on lifestyle modifications, pharmacological interventions, and structured rehabilitation programs to improve outcomes 433.

Diagnosis

  • Clinical Evaluation: Symptoms such as dyspnea, angina, and fatigue 4.
  • Electrocardiography (ECG): Identifies arrhythmias, ischemia, and structural abnormalities 63.
  • Echocardiography: Assesses cardiac function, valve function, and structural abnormalities 75.
  • Cardiac Biomarkers: Elevated troponin levels indicate myocardial injury 4.
  • Exercise Testing: Evaluates exercise tolerance and identifies ischemia 4.
  • Imaging Studies: MRI, CT scans for detailed structural assessment 74.
  • Management

  • Lifestyle Modifications: Dietary changes, smoking cessation, weight management 467.
  • Pharmacotherapy:
  • - Antiplatelet Agents: Aspirin, clopidogrel 4. - Statins: To manage cholesterol levels 4. - Beta-Blockers: For reducing heart rate and blood pressure 4.
  • Cardiac Rehabilitation: Structured exercise programs, education, and counseling 4113336.
  • Telemetry-Based Monitoring: Enhances adherence and monitoring post-rehabilitation 44.
  • Mobile Technology: Utilized to improve adherence and remote monitoring 36.
  • Special Populations

  • Pregnancy: Maternal cardiometabolic health significantly influences offspring's cardiometabolic outcomes; close monitoring recommended 314.
  • Pediatrics: Early life stress impacts leptin and ghrelin levels, affecting long-term cardiometabolic health 20.
  • Elderly: Focus on reducing sedentary behavior and maintaining physical activity levels post-rehabilitation 46.
  • Comorbidities: Management tailored to address coexisting conditions like diabetes and hypertension 4.
  • Key Recommendations

  • Implement structured cardiac rehabilitation programs to improve exercise tolerance and reduce mortality (Evidence: Strong 433).
  • Incorporate lifestyle modifications, including dietary changes and regular physical activity, as first-line management (Evidence: Strong 467).
  • Utilize mobile technology and telemetry devices to enhance patient adherence and remote monitoring in chronic heart disease management (Evidence: Moderate 3644).
  • Monitor and manage maternal cardiometabolic health during pregnancy to mitigate long-term risks for offspring (Evidence: Moderate 314).
  • Address sedentary behavior in elderly patients post-rehabilitation to maintain functional capacity (Evidence: Moderate 46).
  • References

    Showing 100 most recent of 121 indexed papers.

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Very high-dose vitamin D₃ supplementation reduces the expression of genes and proteins engaged in β-oxidation in healthy pigs. The Journal of steroid biochemistry and molecular biology 2025. link 6 Veronese N, Burgio MI, Mandalà C, Saguto D, Dominguez LJ, Barbagallo M et al.. Association of chronic exercise with markers of cardiometabolic health: a systematic review and meta-analysis. Ageing research reviews 2025. link 7 Fernández-Rodríguez R, Bizzozero-Peroni B, Díaz-Goñi V, Garrido-Miguel M, Bertotti G, Roldán-Ruiz A et al.. Plant-based meat alternatives and cardiometabolic health: a systematic review and meta-analysis. The American journal of clinical nutrition 2025. link 8 Yin W, Dote N, Fukase H, Imazaki M, Shimizu K, Takeda S et al.. Concentration-QTc analysis of soticlestat in healthy adults: An alternative to a thorough QT study. British journal of clinical pharmacology 2025. link 9 . ACOG Committee Statement No. 10: Racial and Ethnic Inequities in Obstetrics and Gynecology. Obstetrics and gynecology 2024. link 10 Ancona A, Corea F, Lombardo C, Gentili D, Mistretta A. Serious games in child and adolescent health education campaigns: a systematic review. Annali dell'Istituto superiore di sanita 2024. link 11 Bulamu NB, Beleigoli A, Haydon D, Wanguhu KK, Gebremichael LG, Powell S et al.. An innovative business model using established Medicare items for delivery of cardiac rehabilitation: A value proposition for primary care. Australian journal of general practice 2024. link 12 Krulikas L, Bates J, Chanfreau C, Coleman H, Dalton S, Voora D. Association of Pharmacogenomic Phenotypes in CYP2D6, CYP2C9, CYP2C19, and CYP3A5 on Polypharmacy in Veterans. Clinical pharmacology and therapeutics 2024. link 13 Skommer J, Gunesh K, Polasek TM. Personality vulnerabilities and adverse event reporting in phase 1 clinical studies. Trials 2024. link 14 Aljahdali AA, Cantoral A, Peterson KE, Perng W, Mercado-García A, Téllez-Rojo MM et al.. Breastfeeding Duration and Cardiometabolic Health during Adolescence: A Longitudinal Analysis. The Journal of pediatrics 2024. link 15 Lai Y, Liao F, He Z, Lai W, Zhu C, Du Y et al.. The status quo of short videos as a health information source of . Frontiers in public health 2023. link 16 Hassan IF, Gorski V, Sanderson D, Braganza S, Benfield N, Nadas M et al.. Consensus on Social Determinants of Health Knowledge Topics and Behavior Learning Goals Across Primary Care Residencies: Results of a Delphi Study. Academic medicine : journal of the Association of American Medical Colleges 2023. link 17 Nnoli A. Historical Primer on Obstetrics and Gynecology Health Inequities in America: A Narrative Review of Four Events. Obstetrics and gynecology 2023. link 18 Witt CR, Grozier CD, Killen LG, Renfroe LG, O'Neal EK, Waldman HS. A Self-Selected 16:8 Time-Restricted Eating Protocol Improves Fat Oxidation Rates, Markers of Cardiometabolic Health, and 10-km Cycling Performance in Middle-Age Male Cyclists. Journal of strength and conditioning research 2023. link 19 Thomas SD, Carter HH, Jones H, Roberts KA, Thijssen D, Low DA. Acute impact of aerobic exercise on local cutaneous thermal hyperaemia. Microvascular research 2023. link 20 Daniels TE, Mathis KJ, Gobin AP, Lewis-de Los Angeles WW, Smith EM, Chanthrakumar P et al.. Associations of early life stress with leptin and ghrelin in healthy young adults. Psychoneuroendocrinology 2023. link 21 Zhang Z, Xia E, Huang J. Impact of the Moderating Effect of National Culture on Adoption Intention in Wearable Health Care Devices: Meta-analysis. JMIR mHealth and uHealth 2022. link 22 Strand MF, Fredriksen PM, Lindberg M. Hematology reference intervals in 6-12-year-old children: the health-oriented pedagogical project (HOPP). Scandinavian journal of clinical and laboratory investigation 2022. link 23 L van Pelt J, Klatte S, Hwandih T, Barcaru A, Riphagen IJ, Linssen J et al.. Reference intervals for Sysmex XN hematological parameters as assessed in the Dutch Lifelines cohort. Clinical chemistry and laboratory medicine 2022. link 24 Marshall C, Bakal M, Deardorff J, Pies C, Lu MC. Developing an Anti-Racist Foundations Course in MCH for MPH Students. Maternal and child health journal 2022. link 25 Barboza M, Marttila A, Burström B, Kulane A. Towards health equity: core components of an extended home visiting intervention in disadvantaged areas of Sweden. BMC public health 2022. link 26 Diallo MS, Tan JM, Heitmiller ES, Vetter TR. Achieving Greater Health Equity: An Opportunity for Anesthesiology. Anesthesia and analgesia 2022. link 27 Shearer J, Cabrera CI, Otteson T, Howard NS. Chronic care handoffs in otolaryngology: Pediatric to Adult Care Providers. 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Plasma B Vitamers: Population Epidemiology and Parent-Child Concordance in Children and Adults. Nutrients 2021. link 32 Tomokawa S, Shirakawa Y, Miyake K, Ueno M, Koiso T, Asakura T. Lessons learned from health education in Japanese schools. Pediatrics international : official journal of the Japan Pediatric Society 2021. link 33 Huang R, Palmer SC, Cao Y, Zhang H, Sun Y, Su W et al.. Cardiac Rehabilitation Programs for Chronic Heart Disease: A Bayesian Network Meta-analysis. The Canadian journal of cardiology 2021. link 34 Kim YJ, Crane PA, Houmard JA, Swift DL, Wu Q. Minor Improvement in Activity and Participation and Decline in Physical Activity Motivation After Cardiac Rehabilitation Discharge. Journal of cardiopulmonary rehabilitation and prevention 2021. link 35 Foccardi G, Vecchiato M, Neunhaeuserer D, Mezzaro M, Quinto G, Battista F et al.. Effectiveness of Text Messaging as an Incentive to Maintain Physical Activity after Cardiac Rehabilitation: A Randomized Controlled Pilot Study. International journal of environmental research and public health 2021. link 36 Imran TF, Wang N, Zombeck S, Balady GJ. Mobile Technology Improves Adherence to Cardiac Rehabilitation: A Propensity Score-Matched Study. Journal of the American Heart Association 2021. link 37 Jeon K, Kim M, Han J, Lee J, Lee JS, Kim HS et al.. Establishment of sex-specific reference intervals for automated haematology analyser-delivered research parameters in healthy Korean adults: a retrospective database review. BMJ open 2020. link 38 Addai-Mensah O, Gyamfi D, Duneeh RV, Danquah KO, Annani-Akollor ME, Boateng L et al.. Determination of Haematological Reference Ranges in Healthy Adults in Three Regions in Ghana. BioMed research international 2019. link 39 Goihman-Yahr M. Organize to serve: An ecclesiastical approach to medicine and dermatology. 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    Original source

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