Overview
Micropapillary urothelial carcinoma (MPUC) is a rare histological variant of urothelial carcinoma 1. It is characterized by a distinct papillary architecture with a lack of fibrovascular cores and a dense arrangement of tumor cells 1.Diagnosis
Ex-vivo fluorescent confocal microscopy (FCM) has shown promise in distinguishing cancerous from non-cancerous prostate tissues with an accuracy range of 85.33% to 95.1% 1.
FCM may also be valuable for real-time assessment of surgical margins during radical prostatectomy 1.
One study included in a systematic review focused on bladder cancer and the use of FCM 1.Management
No management strategies are discussed in the provided abstracts.Special Populations
No information on special populations is available in the provided abstracts.Key Recommendations
Ex-vivo fluorescent confocal microscopy (FCM) shows promise in diagnosing prostate cancer with high accuracy 1. (Evidence: Moderate)
FCM may be useful for real-time assessment of surgical margins during radical prostatectomy 1. (Evidence: Moderate)
Further research into the application of FCM in bladder cancer is warranted 1. (Evidence: Weak)References
1 Eissa A, Puliatti S, Rodriguez Peñaranda N, Resca S, Di Bari S, Vella J et al.. Current applications of ex-vivo fluorescent confocal microscope in urological practice: a systematic review of literature. Chinese clinical oncology 2024. link