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Infectious Disease17 papers

Infestation by Sarcoptes scabiei var hominis

Last edited: 4/10/2026

Overview

Scabies is an infestation of the skin by the mite Sarcoptes scabiei var hominis 1. It is characterized by intense itching and a characteristic rash 1.

Diagnosis

  • Diagnosis is primarily clinical, based on the presence of characteristic burrows, papules, and intense pruritus, often worse at night 1.
  • Microscopic identification of mites, eggs, or scybala in skin scrapings can confirm the diagnosis 1.
  • Management

  • First-line treatment typically involves topical scabicides 1.
  • Permethrin cream 5% is a commonly recommended first-line agent 1.
  • Ivermectin, given orally, is an alternative first-line treatment, particularly for widespread infestations or when topical therapy is impractical 1.
  • Treatment should be repeated as per product instructions or guideline recommendations to ensure eradication 1.
  • All close contacts should be treated simultaneously, even if asymptomatic 1.
  • Special Populations

  • The guideline provides recommendations for adults and children aged 13 or above attending sexual health services 1.
  • Key Recommendations

  • Diagnosis is primarily clinical, supported by skin scrapings if necessary 1. (Evidence: Expert opinion)
  • Topical permethrin 5% cream or oral ivermectin are recommended as first-line treatments for scabies 1. (Evidence: Strong)
  • Simultaneous treatment of all household and sexual contacts is crucial for effective control 1. (Evidence: Expert opinion)
  • References

    1 Morris G, Haddow L, Sashidharan PN, Savary-Trathen A, Soni S, Bigland C et al.. British Association for Sexual Health and HIV National Guideline on the Management of Scabies in adults 2025. International journal of STD & AIDS 2025. link

    Original source

    1. [1]
      British Association for Sexual Health and HIV National Guideline on the Management of Scabies in adults 2025.Morris G, Haddow L, Sashidharan PN, Savary-Trathen A, Soni S, Bigland C et al. International journal of STD & AIDS (2025)

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