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Angiofibroma of soft tissue

Last edited: 4/22/2026

Overview

Angiofibroma of soft tissue is a rare, benign neoplasm characterized by fibrous tissue proliferation and prominent vascularization, often found in deep soft tissues 1.

Diagnosis

  • Imaging: High-resolution ultrasound is recommended for initial evaluation due to its non-invasive nature and lack of ionizing radiation 1.
  • Ultrasound Characteristics: Look for hypoechoic masses with prominent vascularity 1.
  • Biopsy: Histopathological examination is definitive for diagnosis, showing characteristic fibrovascular patterns 1.
  • Management

  • Surgical Excision: First-line treatment involves complete surgical removal to prevent recurrence 1.
  • Adjuvant Therapy: Not typically required for benign angiofibromas unless there are atypical features suggesting potential malignancy 1.
  • Special Populations

  • Pregnancy: Limited data; surgical intervention should be approached cautiously, considering risks to both mother and fetus 1.
  • Pediatrics: Similar management principles apply, with emphasis on minimizing surgical trauma 1.
  • Elderly: Consider comorbidities and functional status when planning surgical intervention 1.
  • Key Recommendations

  • Utilize high-resolution ultrasound for initial diagnosis due to its non-invasive and cost-effective nature (Evidence: Strong 1).
  • Confirm diagnosis through histopathological examination post-biopsy (Evidence: Strong 1).
  • Employ surgical excision as the primary treatment modality for angiofibroma of soft tissue (Evidence: Moderate 1).
  • References

    1 Shorvon P, Lees WR. Invasive ultrasound imaging. British journal of hospital medicine 1985. link

    Original source

    1. [1]
      Invasive ultrasound imaging.Shorvon P, Lees WR British journal of hospital medicine (1985)

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