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Dermatology6 papers

Acral fibromyxoma

Last edited: 4/15/2026

Overview

Acral fibromyxoma is a rare benign soft tissue tumor typically occurring in the fingers or toes, characterized by its superficial location and histopathological features of fibroblastic and myxoid components 1.

Diagnosis

  • Clinical presentation often involves a slow-growing, painless nodule on acral sites 1.
  • Histopathologic examination confirms the diagnosis with features of fibroblastic proliferation and myxoid matrix 1.
  • Imaging (e.g., ultrasound, MRI) may help delineate the extent and depth of the lesion 1.
  • Management

  • Surgical excision with clear margins is the primary treatment modality 1.
  • Recurrence is rare if complete excision is achieved 1.
  • Adjuvant therapies are not typically required 1.
  • Special Populations

  • Limited data available; specific considerations for pregnancy, pediatrics, elderly, or comorbidities not addressed in current literature 1.
  • Key Recommendations

  • Confirm diagnosis through histopathological examination of biopsy specimens (Evidence: Expert opinion 1).
  • Perform surgical excision with adequate margins for definitive treatment (Evidence: Expert opinion 1).
  • Monitor for recurrence post-surgery, though it is uncommon with proper excision (Evidence: Expert opinion 1).
  • References

    1 Meyerle JH, Keller RA, Krivda SJ. Superficial acral fibromyxoma of the index finger. Journal of the American Academy of Dermatology 2004. link00761-8)

    Original source

    1. [1]
      Superficial acral fibromyxoma of the index finger.Meyerle JH, Keller RA, Krivda SJ Journal of the American Academy of Dermatology (2004)

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