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Pleural fibroma

Last edited: 4/15/2026

Overview

Pleural fibroma is a rare benign neoplasm arising from pleural mesothelial cells, typically presenting with nonspecific symptoms related to local compression or invasion 2.

Diagnosis

  • Imaging studies (CT, MRI) essential for initial evaluation and localization 2.
  • Thoracoscopy or biopsy required for definitive diagnosis through histological examination 2.
  • Differentiation from malignant lesions crucial, often necessitating immunohistochemical staining 2.
  • Management

  • Surgical resection (thoracoscopic or open thoracotomy) is the primary treatment modality 2.
  • Adjuvant therapy not typically required for benign pleural fibromas 2.
  • Postoperative monitoring for recurrence recommended, though specific protocols not detailed 2.
  • Special Populations

  • No specific management guidelines provided for pregnancy, pediatrics, or elderly populations in the given abstracts [].
  • Comorbidities may influence surgical approach but are not specifically addressed [].
  • Key Recommendations

  • Confirm diagnosis via thoracoscopic biopsy and histological analysis (Evidence: Moderate 2).
  • Employ surgical resection as the mainstay of treatment for symptomatic or suspected malignant transformation 2 (Evidence: Moderate 2).
  • Monitor for recurrence post-surgery, though standardized protocols are not specified 2 (Evidence: Expert opinion).
  • References

    1 Higaki Y, Yoshinaga Y, Kawashima M. Blister formation over a soft fibroma of the nipple. The Journal of dermatology 1993. link 2 Sarica K, Frick J, Doringer E, Chandra I. Ureteral fibroma: an unusual clinical symptomatology. International urology and nephrology 1992. link

    Original source

    1. [1]
      Blister formation over a soft fibroma of the nipple.Higaki Y, Yoshinaga Y, Kawashima M The Journal of dermatology (1993)
    2. [2]
      Ureteral fibroma: an unusual clinical symptomatology.Sarica K, Frick J, Doringer E, Chandra I International urology and nephrology (1992)

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