Overview
General adaptation syndrome (GAS), also known as Selye's syndrome, describes the body's response to stress through three stages: alarm, resistance, and exhaustion. It outlines the physiological and psychological processes individuals undergo when facing stressors.Diagnosis
Management
Special Populations
Key Recommendations
References
Showing 100 most recent of 559 indexed papers.
1 Khondker A, Ahmad I, Dhalla R, Kaushal S, Kwong JCC, Rickard M et al.. The 2025 update on artificial intelligence models in pediatric urology: Results from the AI-PEDURO collaborative. Journal of pediatric urology 2026. link 2 Skoufias E, Vinha K. Community-level externalities in child health: Evidence from Sub-Saharan Africa. PloS one 2026. link 3 Zhang Z. Pharmacological perspectives on integrating sports and medicine: Collaborative models for drug therapy optimization and health promotion. Pakistan journal of pharmaceutical sciences 2026. link 4 Donahue EKF, Baker JD, Donahue SP. The history and evolution of pediatric ophthalmology training: celebrating 50 years of the American Association for Pediatric Ophthalmology and Strabismus. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 2026. link 5 Shapiro J, Grad V, Pulver C, Sanders O, Kanee L, Hoveyda S et al.. A Qualitative Study on the Role of Single-Entry Models in Managing Surgical Backlogs in Pediatric Otolaryngology Part 1: Investigating Perceptions of Referring Physicians and Otolaryngologists. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 2026. link 6 Mckenzie N, Jacobs JW, Milner DA, Lipenga K, Mengwa R, Kawonga E et al.. Clinical pathology and laboratory medicine capacity across a sample of Malawian institutions: a cross-sectional survey. American journal of clinical pathology 2026. link 7 Gopal SH, Hagan JL, Pammi M. Meta-Analysis in Clinical Research: An Overview of the Statistics of Evidence Synthesis. Hospital pediatrics 2025. link 8 Tiamiyu K, Pahwa A, Gates M, Bertram A, Murphy E. Impact of meta-memory techniques in generating effective differential diagnoses in a pediatric core clerkship. Diagnosis (Berlin, Germany) 2025. link 9 Demby A, Laviolette L. Delivering on the promise of better health for women, children, and adolescents. Global health action 2025. link 10 Karnik R, Elder RW. Training pediatric cardiology fellows in the current era of healthcare. Current opinion in pediatrics 2025. link 11 Limon Ö, Doğan NÖ, Limon G, Aksay E. An analysis of sample size calculations in randomized control trials in emergency medicine. The American journal of emergency medicine 2025. link 12 Pashankar DS, Prior D, Arora A, Fekieta R, Marco K, Spatz E et al.. Evaluation and Utility of an Electronic Consultation Program in a Children's Health System. Academic pediatrics 2025. link 13 McGee LM, Soo E, Seideman CA. Integration of novel artificial intelligence tools in pediatric urologic practice. Current opinion in urology 2025. link 14 Spencer KA, Levy B, Martin R, Copeland H, Cranford W, McLouth C et al.. The Road From Abstract to Publication in Pediatric Urology. Urology 2025. link 15 Williamson FA, Lester JN, Mattei JK, Asghar M, Ferrell K, Estrella G et al.. "Safer than driving": Risk communication about surgery with racially diverse families in pediatric urology visits. Patient education and counseling 2025. link 16 't Hoen LA, van Uitert A, Bussmann M, Bezuidenhout C, Ribal M, Canfield S et al.. Annual updates of the European Association of Urology - European Society for Pediatric Urology (EAU-ESPU) paediatric urology guidelines: Are large-language models (LLM) better than the usual structured methodology?. Journal of pediatric urology 2025. link 17 Braga LH, Farrokhyar F, Dönmez Mİ, Nelson CP, Haid B, Herbst K et al.. Randomized controlled trials - The what, when, how and why. Journal of pediatric urology 2025. link 18 Glezerman M, Louwen F, Mahmood T. Gender and Sex Conscious Medicine and the future direction of health care: An invited scientific review by the European Board and College of Obstetrics and Gynaecology (EBCOG). European journal of obstetrics, gynecology, and reproductive biology 2025. link 19 Michnick AI, Barrett K, Brisbane G, McGown S, Nandyala S, Ojo E et al.. Capturing Pediatric Health and Medication Use in a US National Health Data Network. Pharmacoepidemiology and drug safety 2025. link 20 Adhan IK, Sussberg RM, Nelson LB, Lee KE. Revisiting Medicaid Reimbursements and Their Effects on the Economics of Pediatric Ophthalmology Two Years Later. Journal of pediatric ophthalmology and strabismus 2025. link 21 Bahar TS, Öcal O, Çetinkaya Yaprak A. Comparison of ChatGPT-4, Microsoft Copilot, and Google Gemini for Pediatric Ophthalmology Questions. Journal of pediatric ophthalmology and strabismus 2025. link 22 Wiegersma AM, Roseboom TJ, de Rooij SR. Women exposed to famine in early gestation have increased mortality up to age 76 years. Paediatric and perinatal epidemiology 2025. link 23 Curry B, Buttle S, McMillan HJ, Webster R, Reddy D, Karir A et al.. Does E-learning Facilitate Medical Education in Pediatric Neurology?. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2024. link 24 Silverii H, Fernandez N, Ahn J, Lendvay T, Shnorhavorian M, Joyner B et al.. Standardization and Implementation of a Surgical Coaching Model for Pediatric Urology. Journal of surgical education 2024. link 25 Bhardwaj N, Pierre GS, Halloran AP, Alexander TC, Leung SH, Lu Y et al.. Failure to Participate in Sports: An Evaluation of Preparticipation Physicals in a Local School District. Journal of the American Board of Family Medicine : JABFM 2024. link 26 Rojas-Carabali W, Agrawal R, Gutierrez-Sinisterra L, Baxter SL, Cifuentes-González C, Wei YC et al.. Natural Language Processing in medicine and ophthalmology: A review for the 21st-century clinician. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2024. link 27 Gottman DC, Corbisiero MF, Saeedi A, Bothwell S, Svoboda E, Ai A et al.. Assessing robotic-assisted procedures in pediatric otolaryngology: A systematic review and meta-analysis. International journal of pediatric otorhinolaryngology 2024. link 28 Rowland BA, Motamedi V, Michard F, Saha AK, Khanna AK. Impact of continuous and wireless monitoring of vital signs on clinical outcomes: a propensity-matched observational study of surgical ward patients. British journal of anaesthesia 2024. link 29 Wang R, Mehta C. Power Considerations in Designing and Interpreting Adaptive Clinical Trials. NEJM evidence 2024. link 30 Sharma SN, Meller LLT, Sharma AN, Amsterdam EA. Cardiovascular Adaptations of Space Travel: A Systematic Review. Cardiology 2023. link 31 Stern JK, Camus MS. Point-of-Care Instruments. The Veterinary clinics of North America. Small animal practice 2023. link 32 Conry J, Robson S. Climate change and women's health: Turning leadership into action. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2023. link 33 Coşkun A, Sandberg S, Unsal I, Cavusoglu C, Serteser M, Kilercik M et al.. Personalized and Population-Based Reference Intervals for 48 Common Clinical Chemistry and Hematology Measurands: A Comparative Study. Clinical chemistry 2023. link 34 Ghazizadeh H, Kathryn Bohn M, Esmaily H, Boskabadi M, Mohammadi-Bajgiran M, Farahani E et al.. Comparison of reference intervals for biochemical and hematology markers derived by direct and indirect procedures based on the Isfahan cohort study. Clinical biochemistry 2023. link 35 Saleem SG, Ali S, Khatri A, Mukhtar S, Farooq W, Maroof Q et al.. Clinical Outcomes Following the Implementation of a Novel One-Year Training Program in Emergency Medicine in Karachi, Pakistan. Annals of global health 2023. link 36 Williams VW, Finkelstein JB. Speaking and listening: The importance of stakeholder engagement in quality improvement in pediatric urology. Journal of pediatric urology 2023. link 37 Wolfe I, Forman J, Cecil E, Newham J, Hu N, Satherley R et al.. Effect of the Children and Young People's Health Partnership model of paediatric integrated care on health service use and child health outcomes: a pragmatic two-arm cluster randomised controlled trial. The Lancet. Child & adolescent health 2023. link00216-X) 38 Hight D, Kreuzer M, Ugen G, Schuller P, Stüber F, Sleigh J et al.. Five commercial 'depth of anaesthesia' monitors provide discordant clinical recommendations in response to identical emergence-like EEG signals. British journal of anaesthesia 2023. link 39 Heft ME, Wong K, James CA, Lewis PS, Hicks ED, Jensen HK et al.. Establishing a pediatric interventional radiology inpatient consult service. Pediatric radiology 2023. link 40 Jullien S, Mateescu I, Brînzac MG, Dobocan C, Pop I, Weber MW et al.. Unnecessary hospitalisations and polypharmacy practices in Romania: A health system evaluation for strengthening primary health care. Journal of global health 2023. link 41 Xue H, Li M, Fan L, Du W, Zou J. Trends in Adverse Drug Reactions Among Children: Evidence from Jiangsu Province of China, 2010-2019. Paediatric drugs 2023. link 42 Brucia RC, Taggart NW, Sagiv E, Kohli U, Tisma-Dupanovic S, Sutton NJ et al.. Applying Practice Analysis to Develop a New Test Content Outline for the Pediatric Cardiology Certification Examination. Pediatric cardiology 2023. link 43 Peng Y, Zhou Y. Analysis of influencing factors on the duration of pediatric peripheral intravenous catheter. The journal of vascular access 2023. link 44 McHale S, Marufu TC, Manning JC, Taylor N. Reducing failure to rescue rates in a paediatric in-patient setting: A 9-year quality improvement study. Nursing in critical care 2023. link 45 Takahashi N, Matsuhisa T, Takahashi K, Ban N. Diversity of academic general medicine: A cross-sectional bibliometric study of original English-language research articles in general medicine and cardiology in Japan. Medicine 2022. link 46 Peiris R, Cornell S, Greaves K, Bonner C. Do hospital consent forms for cardiology procedures meet health literacy standards? Evaluation of understandability and readability. Patient education and counseling 2022. link 47 Zeidan A, Salhi B, Backster A, Shelton E, Valente A, Safdar B et al.. A Structural Competency Framework for Emergency Medicine Research: Results from a Scoping Review and Consensus Conference. The western journal of emergency medicine 2022. link 48 Paraboschi I, Mantica G, Minoli DG, De Marco EA, Gnech M, Bebi C et al.. Fluorescence-Guided Surgery and Novel Innovative Technologies for Improved Visualization in Pediatric Urology. International journal of environmental research and public health 2022. link 49 Connelly ZM, Abou Ghayda R, Paneque T, Gómez Rivas J, Esperto F, Azzawe A et al.. Online surgical education adopted among urology residency programs in response to COVID-19: A pilot study. Actas urologicas espanolas 2022. link 50 Cohen SA, Pershing S. An evaluation of the content on pediatric ophthalmology fellowship program websites. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 2022. link 51 Rönnberg L, Nilsson U, Hellzén O, Melin-Johansson C. Beyond the monitors: Anaesthesiologists' experiences of the process of extubation. Scandinavian journal of caring sciences 2022. link 52 Pattisapu P, Raol NP. Healthcare Equity in Pediatric Otolaryngology. Otolaryngologic clinics of North America 2022. link 53 Ward LM, Sykora CA, Prakash Y, Cohen MB, Levi JR. Parental Views on the Role of Social Media in Pediatric Otolaryngology. The Annals of otology, rhinology, and laryngology 2022. link 54 Chan SHT, Yu T, Zhang Z, Chang LY, Guo C, Bo Y et al.. Total and differential white blood cell count and cause-specific mortality in 436 750 Taiwanese adults. Nutrition, metabolism, and cardiovascular diseases : NMCD 2022. link 55 Goldfischer ER. Clinical Research 2021. The Urologic clinics of North America 2021. link 56 Amin A, Remme M, Allotey P, Askew I. Gender equality by 2045: reimagining a healthier future for women and girls. BMJ (Clinical research ed.) 2021. link 57 Ardern CL, Cleland JA, Heiderscheit BC, Hughes C, Kamper SJ, Silbernagel K. Celebrating the Achievements of Yet Another Challenging Year. The Journal of orthopaedic and sports physical therapy 2021. link 58 Norsworthy GD, Cook AK, Lanier CJ. Impact of preheparinization and sample volume on routine hematology findings in healthy cats. Journal of feline medicine and surgery 2021. link 59 Çakan M, Karadağ ŞG, Ayaz NA. Differential diagnosis portfolio of a pediatric rheumatologist: eight cases, eight stories. Clinical rheumatology 2021. link 60 Ching CB, Koyle MA. Pediatric Urology and International Medical Volunteerism: Where Are We? Where Are We Going?. Urology 2021. link 61 McClelland D, O'Connor LP, Barnard J, Hajiran A, Crigger C, Trump T et al.. The utilization of perfused cadaver simulation in urologic training: a pilot study. BMC urology 2021. link 62 Jiang DD, Chakiryan NH, Gillis KA, Acevedo AM, Chen Y, Austin JC et al.. Relative value units do not adequately account for operative time in pediatric urology. Journal of pediatric surgery 2021. link 63 Wang M, Liao B, Jian Z, Jin X, Xiang L, Yuan C et al.. Participation in Virtual Urology Conferences During the COVID-19 Pandemic: Cross-sectional Survey Study. Journal of medical Internet research 2021. link 64 Hussain M, Khalique A, Kumar P, Hassan AS, Hashmi A, Rizvi AUH. E-learning in postgraduate urology training: A Covid-19 pandemic experience. JPMA. The Journal of the Pakistan Medical Association 2021. link 65 Wiseso FA, Hendri AZ, Brodjonegoro SR. Implementation of Telemedicine in Indonesian Urology Practice During COVID-19 Pandemic: a National Survey. Urology journal 2021. link 66 Bukowski R, Schulz K, Gaither K, Stephens KK, Semeraro D, Drake J et al.. Computational medicine, present and the future: obstetrics and gynecology perspective. American journal of obstetrics and gynecology 2021. link 67 Alaba OA, Hongoro C, Thulare A, Lukwa AT. Leaving No Child Behind: Decomposing Socioeconomic Inequalities in Child Health for India and South Africa. International journal of environmental research and public health 2021. link 68 Lindvall K, Vaezghasemi M, Feldman I, Ivarsson A, Stevens KJ, Petersen S. Feasibility, reliability and validity of the health-related quality of life instrument Child Health Utility 9D (CHU9D) among school-aged children and adolescents in Sweden. Health and quality of life outcomes 2021. link 69 Obert DP, Schweizer C, Zinn S, Kratzer S, Hight D, Sleigh J et al.. The influence of age on EEG-based anaesthesia indices. Journal of clinical anesthesia 2021. link 70 Dzau VJ, McClellan MB, McGinnis JM, Marx JC, Sullenger RD, ElLaissi W. Vital Directions For Health And Health Care: Priorities For 2021. Health affairs (Project Hope) 2021. link 71 Hanafy A, Seejore K, Lynch J, Murray RD. Interpretation of the endocrinology of hospital inpatients. British journal of hospital medicine (London, England : 2005) 2021. link 72 Yang D, Liu Y, Wang Y, Ma Y, Bai J, Yu C. Association of Serum Vitamin B6 with All-Cause and Cause-Specific Mortality in a Prospective Study. Nutrients 2021. link 73 Cioffi A, Rinaldi R. Does an occupational physician have a duty to carry out general clinical assessments?. The Medico-legal journal 2021. link 74 Finkel L, Paladugu K, Sanyal S, Ghelani S, Colla JS. General Pediatric Clinical Applications of POCUS: Part 1. Pediatric annals 2020. link 75 Mertz L. Updating Diagnoses for Speed and Accuracy: Using AI, Cameras, Assays, and More. IEEE pulse 2020. link 76 Weiss P, Mauer E, Gerber LM, Boyer D, Abramson EL. Funding sources and effects of limited funding in pediatric pulmonology fellowship programs. Pediatric pulmonology 2020. link 77 Pellatt R, Purdy E, Keijzers G. Review article: A primer for clinical researchers in the emergency department: Part XI. Inertia before investigation: Pre-test probability in emergency medicine. Emergency medicine Australasia : EMA 2020. link 78 Ebert JF, Huibers L, Christensen B, Collatz Christensen H, Christensen MB. Does an emergency access button increase the patients' satisfaction and feeling of safety with the out-of-hours health services? A randomised controlled trial in Denmark. BMJ open 2020. link 79 Dandena F, Leulseged B, Suga Y, Teklewold B. Magnitude and Pattern of Inpatient Surgical Mortality in a Tertiary Hospital in Addis Ababa, Ethiopia. Ethiopian journal of health sciences 2020. link 80 Weiner PR, Salib A. Developing a men's health program. The Canadian journal of urology 2020. link 81 Tur AB, Prieto JC, Gómez-Fraile A, Corbetta JP. The effect of the Covid-19 Pandemic on pediatric urology. International braz j urol : official journal of the Brazilian Society of Urology 2020. link 82 O'Kelly F, Farhat WA, Koyle MA. Cost, training and simulation models for robotic-assisted surgery in pediatric urology. World journal of urology 2020. link 83 . Implementing Telehealth in Practice. Obstetrics and gynecology 2020. link 84 Tusting LS, Gething PW, Gibson HS, Greenwood B, Knudsen J, Lindsay SW et al.. Housing and child health in sub-Saharan Africa: A cross-sectional analysis. PLoS medicine 2020. link 85 Traseira R, Singh S. Exploring parents' perceptions on the importance and feasibility of child-centred consultations of 5-11 year olds in general practice. Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors 2020. link 86 Bardanzellu F, Fanos V. How could metabolomics change pediatric health?. Italian journal of pediatrics 2020. link 87 Hall ECR, Murgatroyd C, Stebbings GK, Cunniffe B, Harle L, Salter M et al.. The Prospective Study of Epigenetic Regulatory Profiles in Sport and Exercise Monitored Through Chromosome Conformation Signatures. Genes 2020. link 88 Silva CSMD, Pereira Á, Silva PSD, Figueiredo NMA. Men's knowledge on body care: a cartographic study. Revista brasileira de enfermagem 2020. link 89 Mishra K, Boland MV, Woreta FA. Incorporating a virtual curriculum into ophthalmology education in the coronavirus disease-2019 era. Current opinion in ophthalmology 2020. link 90 Van Hout CV, Tachmazidou I, Backman JD, Hoffman JD, Liu D, Pandey AK et al.. Exome sequencing and characterization of 49,960 individuals in the UK Biobank. Nature 2020. link 91 Munjal T, Kavanagh KR, Ezzibdeh RM, Valdez TA. The impact of COVID-19 on global disparities in surgical training in pediatric otolaryngology. International journal of pediatric otorhinolaryngology 2020. link 92 Szulecki D. Going the Extra Mile for Seniors. The American journal of nursing 2020. link 93 Jaqua EE, Chi R, Labib W, Uribe M, Najarro J, Hanna M. Optimize your documentation to improve Medicare reimbursement. Cleveland Clinic journal of medicine 2020. link 94 Kaneko S, Nagashima T. Drug Repositioning and Target Finding Based on Clinical Evidence. Biological & pharmaceutical bulletin 2020. link 95 Ambrose MJ, Walton EA. Improving Health and Safety at Camp. Pediatrics 2019. link 96 Craig JC. Interpreting trial results-time for confidence and magnitude and not P values please. Kidney international 2019. link 97 . Health and medical research for all: The challenge remains open. PLoS medicine 2019. link 98 Basu A, Veenstra DL, Carlson JJ, Wang WJ, Branch K, Probstfield J. How can clinical researchers quantify the value of their proposed comparative research?. American heart journal 2019. link 99 Abbasi U, Chowdhury P, Subramaniam S, Jain P, Muthe N, Sheikh F et al.. A cartridge based Point-of-Care device for complete blood count. Scientific reports 2019. link 100 Long E, Craig S, Babl FE, Tavender E, Lunny C. Review article: A primer for clinical researchers in the emergency department: Part IX. How to conduct a systematic review in the field of emergency medicine. 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