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Psychiatry1310 papers

Substance use disorder

Last edited: 4/23/2026

Overview

Substance use disorder (SUD) encompasses a spectrum of conditions characterized by the harmful or hazardous use of psychoactive substances leading to impairment in daily functioning. It includes alcohol, illicit drugs, and prescription medications misused beyond medical purposes 1234567891011121314151617181920212223242526272829303132333435363738394041424344454647484950515253545556575859606162636465666768697071727374.

Diagnosis

  • Clinical Criteria: Presence of problematic substance use leading to significant impairment or distress 1234567891011121314151617181920212223242526272829303132333435363738394041424344454647484950515253545556575859606162636465666768697071727374.
  • Screening Tools: Use validated tools such as AUDIT, DAST-20, or CAGE for alcohol and drug use disorders 1234567891011121314151617181920212223242526272829303132333435363738394041424344454647484950515253545556575859606162636465666768697071727374.
  • Laboratory Tests: Toxicology screens to confirm substance use 1234567891011121314151617181920212223242526272829303132333435363738394041424344454647484950515253545556575859606162636465666768697071727374.
  • Management

  • First-Line Treatments:
  • - Behavioral Therapies: Cognitive Behavioral Therapy (CBT), Motivational Interviewing 1234567[

    References

    Showing 100 most recent of 225 indexed papers.

    1 Fitzsimons MG, Saddawi-Konefka D, Herman J, Arnholz S, Gottlieb A, Baker KH. A framework for success: Compassionate interventions to support healthcare colleagues when concerns arise. Journal of clinical anesthesia 2026. link 2 Stojanova J, Choy EBK, Brett J, Carland JE, Malek N, Day RO et al.. Equity and quality use of medicines in people who present to the Psychiatric Alcohol and Non-Prescription Drug Assessment Unit. British journal of clinical pharmacology 2026. link 3 Syed OA, Nestor SM, Husain MI, Sinyor M, Alam F, Giacobbe P. Adverse events associated with classic psychedelics and MDMA: a real-world population-based study using the WHO pharmacovigilance database (VigiBase). Psychiatry research 2026. link 4 Xing W, Wu W, Wu J, Cai K, Wang Q, Zhang M et al.. The behavioral characteristics of addiction and mental disorder caused by dextromethorphan abuse were analyzed in multiple dimensions. Expert opinion on drug safety 2026. link 5 Darouiche K, Devin S, Valdebenito S, Ajasin D, Eugenin E. Cocaine-Induced Cardiovascular and Immune Dysfunction: Emerging Mechanisms. Physiology (Bethesda, Md.) 2026. link 6 Blyth SH, Haq R, Menon S, King B, Torres Quesada G, Borodge D et al.. Evidence for safety and tolerability of transcranial magnetic stimulation for substance use disorders. Brain stimulation 2025. link 7 Helvacı Çelik FG, Bayrak NG, Uzun S. Effectiveness of Psychosocial Interventions in Alcohol and Substance Use Disorders: A Meta-Analysis Study. Public health nursing (Boston, Mass.) 2025. link 8 Loften A, Farokhnia M, Vendruscolo LF, Leggio L. Neuroendocrinology meets addiction: Emerging pharmacotherapies on the horizon. Journal of internal medicine 2025. link 9 Schölin L, Humphries C, Eddleston M, Brennan G, Lloyd A, Reed MJ et al.. De-siloing substance misuse and self-harm research through integrated public health and emergency medicine. The Lancet. Public health 2025. link00096-9) 10 Boyd J. "Basically every safety protocol we have in place to protect against overdose, parents can't access": Mothers who use unregulated drugs' experiences of dual public health emergencies. The International journal on drug policy 2025. link 11 Barker B, Norton A, Wood S, Macevicius C, Hogan K, Cadieux K et al.. Implementation of risk mitigation prescribing during dual public health emergencies: A qualitative study among Indigenous people who use drugs and health planners in Northern British Columbia, Canada. The International journal on drug policy 2025. link 12 Alhalaseh L, Abushams L, Qudah R, Van Hout MC, Wazaify M. Substance Use and Misuse Among Older Adults: A Scoping Review. Substance use & misuse 2025. link 13 Tiesman HM, Hendricks S. Suicides and Overdoses at Work: Census of Fatal Occupational Injuries, 2011-2022. American journal of preventive medicine 2025. link 14 Peyrière H, Batisse A, Sam-Laï NF, Daveluy A, Fournier-Choma C, Deheul S et al.. Contribution of Addictovigilance data to assess adverse-events linked to psychoactive substances in children and adolescents. British journal of clinical pharmacology 2025. link 15 Middeldorp JFM, Krijnen-de Bruin E, Buwalda VJA, Goudriaan AE, van Meijel B. Nurse-Led Physical Screening of Patients With Substance Use Disorders: A Cross-Sectional Study. Journal of psychiatric and mental health nursing 2025. link 16 Winterlind EL, Malone SG, Setzer MR, Murphy MA, Saunders D, Gray JC. N-acetylcysteine as a treatment for substance use cravings: A meta-analysis. Addiction biology 2024. link 17 Mehta DD, Praecht A, Ward HB, Sanches M, Sorkhou M, Tang VM et al.. A systematic review and meta-analysis of neuromodulation therapies for substance use disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2024. link 18 Fascher M, Nowaczynski S, Spindler C, Strobach T, Muehlhan M. Neural underpinnings of response inhibition in substance use disorders: weak meta-analytic evidence for a widely used construct. Psychopharmacology 2024. link 19 Danigno JF, Dias MDS, Horta BL. Sense of coherence and substance use in adults: a systematic review and meta-analysis. Cadernos de saude publica 2024. link 20 Oliva HNP, Prudente TP, Nunes EJ, Cosgrove KP, Radhakrishnan R, Potenza MN et al.. Substance use and spine density: a systematic review and meta-analysis of preclinical studies. Molecular psychiatry 2024. link 21 Ebrahimi CT, Song H, Machado M, Segura P, Espinosa A, Polanco-Roman L. Racism-related experiences and substance use: A systematic and meta-analytic review. Social science & medicine (1982) 2024. link 22 Price O, Swanton R, Grebely J, Hajarizadeh B, Webb P, Peacock A et al.. Vaccination coverage among people who inject drugs: A systematic review. The International journal on drug policy 2024. link 23 Randall EJ. Integrating Fitness Equipment in Persistent Traumatic Stress Environments for Reducing Drug Overdoses. Current sports medicine reports 2024. link 24 Taha S, King S, Atif S, Bate E. Changes in harm reduction service providers professional quality of life during dual public health emergencies in Canada. Harm reduction journal 2024. link 25 McCall J, Hobbs H, Ranger C, Cameron F, Stuart H, Nelken J et al.. Prescribed safer supply during dual public health emergencies: a qualitative study examining service providers perspectives on early implementation. Substance abuse treatment, prevention, and policy 2024. link 26 Maher EJ, Stoner SA, Gerlinger J, Ferraro AC, Lepper-Pappan H. Study protocol for a randomized controlled trial of the Parent-Child Assistance Program: a case management and home visiting program for people using substances during pregnancy. Trials 2024. link 27 Fitzsimons MG. Ethics and Management of Substance Use Disorders in Anesthesiology: Detection, Intervention, and Treatment Through Recovery and Return. Anesthesiology clinics 2024. link 28 Foli KJ, Forster AK, Bostic LA, Zhang L, Zhang Z, Stone L. Predictors of Substance Use Risk in Nurse Anesthetists. Journal of addictions nursing 2024. link 29 Carter T, Wingo N, McMullan S, Childs G, Roche B, Merlo LJ et al.. Challenges for Nurse Anesthetists Reentering Practice Following Substance Use Disorder Treatment. AANA journal 2024. link 30 Webb L, Yarwood G, Witham G, Wright S, Galvani S. Providing holistic end-of-life care for people with a history of problem substance use: a mixed methods cohort study of interdisciplinary service provision and integrated care. BMC palliative care 2024. link 31 Kwan ATH, Rosenblat JD, Mansur RB, Teopiz KM, McIntyre RS. The association between ketamine and esketamine with alcohol and substance misuse: Reports to the Food and Drug Administration adverse event reporting system (FAERS). Journal of affective disorders 2024. link 32 Stellern J, Xiao KB, Grennell E, Sanches M, Gowin JL, Sloan ME. Emotion regulation in substance use disorders: a systematic review and meta-analysis. Addiction (Abingdon, England) 2023. link 33 Fogo RC, Martins-da-Silva AS, Blaas IK, Galvão LP, Hasegawa EH, Castaldelli FI et al.. Exploring correlates of involuntary treatment in substance use disorders: a global systematic review and meta-analysis. International review of psychiatry (Abingdon, England) 2023. link 34 . A Majority of U.S. Adults Have Experienced the Impact of Substance Use Disorders. The American journal of nursing 2023. link 35 . Overdose Deaths in Pregnant and Postpartum Women Rose Sharply in 2020. The American journal of nursing 2023. link 36 Giang K, Charlesworth R, Thulien M, Mulholland A, Barker B, Brar R et al.. Risk mitigation guidance and safer supply prescribing among young people who use drugs in the context of COVID-19 and overdose emergencies. The International journal on drug policy 2023. link 37 Beck McGreevy P, Wood S, Thomson E, Burmeister C, Spence H, Pelletier J et al.. Doing community-based research during dual public health emergencies (COVID and overdose). Harm reduction journal 2023. link 38 Kravitz E, Suh M, Russell M, Ojeda A, Levison J, McKinney J. Screening for Substance Use Disorders during Pregnancy: A Decision at the Intersection of Racial and Reproductive Justice. American journal of perinatology 2023. link 39 Sternberger L, Sorensen-Alawad A, Prescott T, Sakai H, Brown K, Finkelstein N et al.. Lessons Learned Serving Pregnant, Postpartum, and Parenting People with Substance Use Disorders in Massachusetts: The Moms Do Care Program. Maternal and child health journal 2023. link 40 Akbarali S, Dronamraju R, Simon J, Echols A, Collins S, Kaeberle B et al.. Promoting Innovation in State and Territorial Maternal and Child Health Policymaking. Maternal and child health journal 2023. link 41 Galvani S, Wright S, Clayson A. Towards a Dignified Death: A New Approach to Care for People Using Substances Who Are at, or Near, the End of Their Lives. International journal of environmental research and public health 2023. link 42 Vafaie N, Kober H. Association of Drug Cues and Craving With Drug Use and Relapse: A Systematic Review and Meta-analysis. JAMA psychiatry 2022. link 43 Honkalampi K, Jokela M, Lehto SM, Kivimäki M, Virtanen M. Association between alexithymia and substance use: A systematic review and meta-analysis. Scandinavian journal of psychology 2022. link 44 Laitano HV, Ely A, Sordi AO, Schuch FB, Pechansky F, Hartmann T et al.. Anger and substance abuse: a systematic review and meta-analysis. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 2022. link 45 Hoch AM, Schoenberger SF, Boyle TP, Hadland SE, Gai MJ, Bagley SM. Attitudes and training related to substance use in pediatric emergency departments. Addiction science & clinical practice 2022. link 46 Bechard M, Cloutier P, Lima I, Salamatmanesh M, Zemek R, Bhatt M et al.. Cannabis-related emergency department visits by youths and their outcomes in Ontario: a trend analysis. CMAJ open 2022. link 47 Madora M, Wetzler S, Jose A, Bernstein PS. Pregnant and Postpartum People with Substance Use Disorders: Understanding the Obstetrical Care Provider' s Roles and Responsibilities. Maternal and child health journal 2022. link 48 Rupprecht N. The Impaired Anesthesia Provider: Strategies to Prevent, Recognize, and Treat Substance Use Disorder within the Workplace. AANA journal 2022. link 49 Misra U, Gilvarry E, Marshall J, Hall R, McLure H, Mayall R et al.. Substance use disorder in the anaesthetist: Guidelines from the Association of Anaesthetists: Guidelines from the Association of Anaesthetists. Anaesthesia 2022. link 50 Cook O, Doran J, Crosbie K, Sweeney P, Millard I, O'Connor M. Palliative care needs and models of care for people who use drugs and/or alcohol: A mixed methods systematic review. Palliative medicine 2022. link 51 Bemanian M, Chowdhury R, Stokke K, Aas CF, Johansson KA, Vold JH et al.. Vitamin D status and associations with substance use patterns among people with severe substance use disorders in Western Norway. Scientific reports 2022. link 52 Gagnon LR, Sadasivan C, Perera K, Oudit GY. Cardiac Complications of Common Drugs of Abuse: Pharmacology, Toxicology, and Management. The Canadian journal of cardiology 2022. link 53 Vrijen C, Wiertsema M, Ackermans MA, van der Ploeg R, Kretschmer T. Childhood and Adolescent Bullying Perpetration and Later Substance Use: A Meta-analysis. Pediatrics 2021. link 54 Fast D. Going Nowhere: Ambivalence about Drug Treatment during an Overdose Public Health Emergency in Vancouver. Medical anthropology quarterly 2021. link 55 Mitchell-Foster SM, Emon CE, Brouwer M, Duncan Elder L, King J. Disconnected perspectives: Patient and care provider's experiences of substance use in pregnancy. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2021. link 56 Baird CR. Substance use disorder in anaesthetists: A personal perspective. Anaesthesia and intensive care 2021. link 57 Chua IS, Fratt E, Ho JJ, Roldan CS, Gundersen DA, Childers J. Primary Addiction Medicine Skills for Hospice and Palliative Medicine Physicians: A Modified Delphi Study. Journal of pain and symptom management 2021. link 58 Mahgoub AE, Deliwala SS, Bachuwa G. Important reminder: nitrous oxide (N. BMJ case reports 2021. link 59 Springer SA, Barocas JA, Wurcel A, Nijhawan A, Thakarar K, Lynfield R et al.. Federal and State Action Needed to End the Infectious Complications of Illicit Drug Use in the United States: IDSA and HIVMA's Advocacy Agenda. The Journal of infectious diseases 2020. link 60 Wainwright JJ, Mikre M, Whitley P, Dawson E, Huskey A, Lukowiak A et al.. Analysis of Drug Test Results Before and After the US Declaration of a National Emergency Concerning the COVID-19 Outbreak. JAMA 2020. link 61 Smid MC, Schauberger CW, Terplan M, Wright TE. Early lessons from maternal mortality review committees on drug-related deaths-time for obstetrical providers to take the lead in addressing addiction. American journal of obstetrics & gynecology MFM 2020. link 62 Aly SM, Omran A, Gaulier JM, Allorge D. Substance abuse among children. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 2020. link 63 Cummings JR, Gearhardt AN. Prospective associations between parental substance use and youth highly processed food intake in the Fragile Families and Child Wellbeing Study. Drug and alcohol dependence 2020. link 64 Warner DO, Berge K, Sun H, Harman A, Wang T. Substance Use Disorder in Physicians after Completion of Training in Anesthesiology in the United States from 1977 to 2013. Anesthesiology 2020. link 65 Szulecki D. Helping Students See the Realities of Addiction and Recovery. The American journal of nursing 2019. link 66 Hawk KF, Glick RL, Jey AR, Gaylor S, Doucet J, Wilson MP et al.. Emergency Medicine Research Priorities for Early Intervention for Substance Use Disorders. The western journal of emergency medicine 2019. link 67 Mull CC, Thompson AD, Rappaport DI, Gartner JC, Bowman WR. A Call to Restore Your Calling: Self-Care of the Emergency Physician in the Face of Life-Changing Stress-Part 3 of 6: Physician Illness and Impairment. Pediatric emergency care 2019. link 68 Kim PC, Yoo JW, Cochran CR, Park SM, Chun S, Lee YJ et al.. Trends and associated factors of use of opioid, heroin, and cannabis among patients for emergency department visits in Nevada: 2009-2017. Medicine 2019. link 69 Jarlenski M, Minney S, Hogan C, Chang JC. Obstetric and Pediatric Provider Perspectives on Mandatory Reporting of Prenatal Substance Use. Journal of addiction medicine 2019. link 70 Van Pelt M, Meyer T, Garcia R, Thomas BJ, Litman RS. Drug Diversion in the Anesthesia Profession: How Can Anesthesia Patient Safety Foundation Help Everyone Be Safe? Report of a Meeting Sponsored by the Anesthesia Patient Safety Foundation. AANA journal 2019. link 71 Witham G, Galvani S, Peacock M. End of life care for people with alcohol and drug problems: Findings from a Rapid Evidence Assessment. Health & social care in the community 2019. link 72 Geller AI, Dowell D, Lovegrove MC, McAninch JK, Goring SK, Rose KO et al.. U.S. Emergency Department Visits Resulting From Nonmedical Use of Pharmaceuticals, 2016. American journal of preventive medicine 2019. link 73 Rosenbloom DL. Commentary on "Gaps in the Substance Use Disorder Treatment Referral Process: Provider Perceptions". Journal of addiction medicine 2018. link 74 Ndimbii J, Ayon S, Abdulrahman T, Mahinda S, Jeneby F, Armstrong G et al.. Access and utilisation of reproductive, maternal, neonatal and child health services among women who inject drugs in coastal Kenya: Findings from a qualitative study. Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives 2018. link 75 Melendez-Torres GJ, Tancred T, Fletcher A, Thomas J, Campbell R, Bonell C. Does integrated academic and health education prevent substance use? Systematic review and meta-analyses. Child: care, health and development 2018. link 76 Straussner SLA, Fewell CH. A review of recent literature on the impact of parental substance use disorders on children and the provision of effective services. Current opinion in psychiatry 2018. link 77 Luo A, Zhang X, Li S, Zhao Y. Sevoflurane addiction due to workplace exposure: A case report and literature review. Medicine 2018. link 78 Bryson EO. The opioid epidemic and the current prevalence of substance use disorder in anesthesiologists. Current opinion in anaesthesiology 2018. link 79 Fitzsimons MG, Baker K, Malhotra R, Gottlieb A, Lowenstein E, Zapol WM. Reducing the Incidence of Substance Use Disorders in Anesthesiology Residents: 13 Years of Comprehensive Urine Drug Screening. Anesthesiology 2018. link 80 . Dental, drugs &drink - A risky cocktail?. British dental journal 2017. link 81 Inci R, Kelekci KH, Oguz N, Karaca S, Karadas B, Bayrakci A. Dermatological aspects of synthetic cannabinoid addiction. Cutaneous and ocular toxicology 2017. link 82 Ip EJ, Yadao MA, Shah BM, Doroudgar S, Perry PJ, Tenerowicz MJ et al.. Polypharmacy, Infectious Diseases, Sexual Behavior, and Psychophysical Health Among Anabolic Steroid-Using Homosexual and Heterosexual Gym Patrons in San Francisco's Castro District. Substance use & misuse 2017. link 83 Bhalla IP, Stefanovics EA, Rosenheck RA. Clinical Epidemiology of Single Versus Multiple Substance Use Disorders: Polysubstance Use Disorder. Medical care 2017. link 84 Hawkins EJ, Malte CA, Hagedorn HJ, Berger D, Frank A, Lott A et al.. Survey of Primary Care and Mental Health Prescribers' Perspectives on Reducing Opioid and Benzodiazepine Co-Prescribing Among Veterans. Pain medicine (Malden, Mass.) 2017. link 85 Allemann SS, Dürsteler KM, Strasser J, Vogel M, Stoeckle M, Hersberger KE et al.. Novel remote electronic medication supply model for opioid-dependent outpatients with polypharmacy--first long-term case study. 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Screening and Brief Interventions for Alcohol and Other Drug Use Among Pregnant Women Attending Midwife Obstetric Units in Cape Town, South Africa: A Qualitative Study of the Views of Health Care Professionals. Journal of midwifery & women's health 2015. link 97 Warner DO, Berge K, Sun H, Harman A, Hanson A, Schroeder DR. Risk and Outcomes of Substance Use Disorder among Anesthesiology Residents: A Matched Cohort Analysis. Anesthesiology 2015. link 98 Fry RA, Fry LE, Castanelli DJ. A retrospective survey of substance abuse in anaesthetists in Australia and New Zealand from 2004 to 2013. Anaesthesia and intensive care 2015. link 99 Choo EK, Beauchamp G, Beaudoin FL, Bernstein E, Bernstein J, Bernstein SL et al.. A research agenda for gender and substance use disorders in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2014. link 100 Rose JS, Campbell M, Skipper G. 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    Original source

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