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Squamous cell carcinoma of head and/or neck

Last edited: 4/10/2026

Overview

Squamous cell carcinoma (SCC) of the head and neck encompasses a group of cancers arising from the squamous cells lining the oral cavity, pharynx, and larynx. These cancers represent a significant public health concern, with treatment and survivorship care requiring a multidisciplinary approach 1.

Diagnosis

  • Diagnosis is typically made via biopsy and histopathological examination 1.
  • Staging is crucial for treatment planning and prognosis 1.
  • Management

  • Treatment strategies are individualized based on cancer stage, location, and patient factors 1.
  • Management may involve surgery, radiation therapy, chemotherapy, or a combination of these modalities 1.
  • Survivorship care focuses on monitoring for recurrence, screening for second primary cancers, and managing long-term and late effects of treatment 1.
  • Key Recommendations

  • Survivorship care should include monitoring for recurrence 1. (Evidence: Expert opinion)
  • Survivorship care should include screening for second primary cancers 1. (Evidence: Expert opinion)
  • Survivorship care should include assessment and management of long-term and late effects of treatment 1. (Evidence: Expert opinion)
  • Survivorship care should include health promotion 1. (Evidence: Expert opinion)
  • Survivorship care should include care coordination 1. (Evidence: Expert opinion)
  • References

    1 Cohen EE, LaMonte SJ, Erb NL, Beckman KL, Sadeghi N, Hutcheson KA et al.. American Cancer Society Head and Neck Cancer Survivorship Care Guideline. CA: a cancer journal for clinicians 2016. link

    Original source

    1. [1]
      American Cancer Society Head and Neck Cancer Survivorship Care Guideline.Cohen EE, LaMonte SJ, Erb NL, Beckman KL, Sadeghi N, Hutcheson KA et al. CA: a cancer journal for clinicians (2016)

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