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Episode of harmful use of psychoactive substance

Last edited: 4/10/2026

Overview

Harmful use of psychoactive substances refers to a pattern of substance use that leads to significant harm, including health problems (physical or mental) and impairment in social functioning 1. This encompasses a range of conditions from substance abuse to dependence 1.

Diagnosis

  • Diagnosis is based on a pattern of use leading to clinically significant impairment or distress, manifested by 1:
  • * Failure to fulfill major role obligations at work, school, or home. * Recurrent use in situations where it is physically hazardous. * Recurrent substance-related legal problems. * Continued use despite persistent or recurrent social or interpersonal problems.
  • Severity specifiers (mild, moderate, severe) can be applied based on the number of criteria met 1.
  • Management

  • Treatment approaches are individualized and may include behavioral therapies, counseling, and pharmacotherapy 1.
  • Motivational interviewing and cognitive behavioral therapy are commonly used 1.
  • Pharmacological interventions are often used to manage withdrawal symptoms and cravings, or to treat co-occurring mental health conditions 1.
  • Special Populations

  • Management in pregnant women requires careful consideration of risks to both mother and fetus, often involving specialized perinatal substance use treatment programs 1.
  • Adolescents may require tailored interventions that address developmental factors and family dynamics 1.
  • Key Recommendations

  • Assessment of harmful psychoactive substance use should include evaluation for health problems and social impairment 1. (Evidence: Expert opinion)
  • Treatment plans should be individualized and may incorporate behavioral therapies and pharmacotherapy 1. (Evidence: Expert opinion)
  • Specialized care is recommended for pregnant women and adolescents with harmful substance use 1. (Evidence: Expert opinion)
  • References

    1 Provencher MT, Brand JC, Rossi MJ, Lubowitz JH. Are Orthopaedic Systematic Reviews Overly Prevalent?. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2016. link

    Original source

    1. [1]
      Are Orthopaedic Systematic Reviews Overly Prevalent?Provencher MT, Brand JC, Rossi MJ, Lubowitz JH Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association (2016)
    2. [2]
      Emergency physicians' duty to warn and protect: a critique and guidelines.Pointer JE, Small LB The Journal of emergency medicine (1986)

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