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Emergency Medicine23 papers

Episode of harmful use of methanol

Last edited: 4/10/2026

Overview

Methanol poisoning is a rare but dangerous condition that can lead to severe outcomes, including kidney injury 1. Prompt recognition and management are crucial for patient survival and minimizing long-term sequelae 1.

Diagnosis

  • Diagnosis is based on clinical suspicion and laboratory confirmation of methanol in the blood or urine 1.
  • Key laboratory findings may include an elevated osmolar gap, metabolic acidosis, and elevated serum methanol levels 1.

    • Management

  • Emergent management may require kidney replacement therapy 1.
  • Treatment strategies for toxic alcohol poisoning, including methanol, are discussed in the literature 1.

    • Key Recommendations

  • Emergent management of methanol poisoning may require kidney replacement therapy 1. (Evidence: Moderate)

    • References

    1 Wang C, Hiremath S, Sikora L, Kanji S, Bugeja A, Samaha D et al.. Kidney outcomes after methanol and ethylene glycol poisoning: a systematic review and meta-analysis. Clinical toxicology (Philadelphia, Pa.) 2023. link

    Original source

    1. [1]
      Kidney outcomes after methanol and ethylene glycol poisoning: a systematic review and meta-analysis. — Wang C, Hiremath S, Sikora L, Kanji S, Bugeja A, Samaha D et al. Clinical toxicology (Philadelphia, Pa.) (2023)
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