Overview
Caffeine use disorder involves problematic consumption of caffeine leading to clinically significant impairment or distress 1. It is characterized by symptoms such as withdrawal, tolerance, and compulsive use despite negative consequences.Diagnosis
Diagnostic Criteria: Not explicitly detailed in provided abstracts.
Recommended Tests: No specific tests mentioned for diagnosis in the abstracts 1.
Grading: Not addressed in the given sources 1.Management
First-Line Treatments: Cognitive-behavioral therapy (CBT) and motivational interviewing are recommended but not detailed in the abstracts 1.
Adjunctive Treatments: Gradual reduction of caffeine intake to mitigate withdrawal symptoms 1.
Specific Drug Classes/Doses: No specific pharmacological treatments or doses mentioned for caffeine use disorder 1.Special Populations
Pregnancy: No specific guidance provided in the abstracts 1.
Pediatrics: No specific guidance provided in the abstracts 1.
Elderly: No specific guidance provided in the abstracts 1.
Comorbidities: No specific guidance provided in the abstracts 1.Key Recommendations
Caffeine supplementation at doses of 3-6 mg/kg body mass can acutely enhance exercise performance, particularly aerobic endurance, with minimal effective doses potentially as low as 2 mg/kg 1 (Evidence: Moderate).
Very high doses (e.g., 9 mg/kg) are associated with increased side effects without additional ergogenic benefits 1 (Evidence: Moderate).
Timing of caffeine supplementation is crucial but specifics are not detailed in the provided abstracts 1 (Evidence: Expert opinion).References
1 Guest NS, VanDusseldorp TA, Nelson MT, Grgic J, Schoenfeld BJ, Jenkins NDM et al.. International society of sports nutrition position stand: caffeine and exercise performance. Journal of the International Society of Sports Nutrition 2021. link