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Neisseria gonorrhoeae proctitis

Last edited: 4/10/2026

Overview

Neisseria gonorrhoeae proctitis is an inflammatory syndrome of the anal canal and/or rectum caused by gonococcal infection 1. It can be transmitted via genital-anal mucosal contact, digital contact, or toys 1. The majority of gonococcal rectal infections are asymptomatic and detected only by laboratory testing 1.

Diagnosis

  • Symptoms may include anorectal itching, pain, tenesmus, bleeding, constipation, and discharge 1.
  • A presumptive diagnosis is made based on symptoms and signs, with a definitive diagnosis confirmed by laboratory tests 1.
  • Exclusion of anorectal infections is indicated with a history of receptive anal contact as part of standard STI screening 1.

    • Management

    Treatment recommendations for N. gonorrhoeae* proctitis are not detailed in the provided abstracts.

    Special Populations

  • No specific information is provided for special populations.

    • Key Recommendations

  • Proctitis is defined as an inflammatory syndrome of the anal canal and/or the rectum 1. (Evidence: Expert opinion)
  • Neisseria gonorrhoeae is a common sexually transmitted anorectal pathogen 1. (Evidence: Expert opinion)
  • The majority of rectal chlamydia and gonococcal infections are asymptomatic and can only be detected by laboratory tests 1. (Evidence: Expert opinion)

    • References

    1 de Vries HJC, Nori AV, Kiellberg Larsen H, Kreuter A, Padovese V, Pallawela S et al.. 2021 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens. Journal of the European Academy of Dermatology and Venereology : JEADV 2021. link

    Original source

    1. [1]
      2021 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens. — de Vries HJC, Nori AV, Kiellberg Larsen H, Kreuter A, Padovese V, Pallawela S et al. Journal of the European Academy of Dermatology and Venereology : JEADV (2021)
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