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Pediatrics7 papers

Arthritis caused by vaccine

Last edited: 4/10/2026

Overview

Vaccinations are crucial for individuals with rheumatic and musculoskeletal diseases (RMDs) due to their increased risk of vaccine-preventable illnesses and potential for severe outcomes 23. Guidelines aim to provide evidence-based recommendations for optimal vaccine use in this population 23.

Diagnosis

Management

  • Guidance is provided on whether to hold immunosuppressive medications or delay vaccination to maximize vaccine immunogenicity and efficacy 23.
  • Safe approaches for using live attenuated vaccines in patients taking immunosuppressive medications are addressed 23.

    • Special Populations

    Key Recommendations

  • The guideline provides expanded indications for certain vaccines in patients with RMDs 23. (Evidence: Expert opinion)
  • Recommendations address the timing of vaccination relative to immunosuppressive medication use to optimize vaccine response 23. (Evidence: Expert opinion)
  • Safe administration of live attenuated vaccines in patients on immunosuppressive therapy is detailed 23. (Evidence: Expert opinion)

    • References

    1 Price O, Swanton R, Grebely J, Hajarizadeh B, Webb P, Peacock A et al.. Vaccination coverage among people who inject drugs: A systematic review. The International journal on drug policy 2024. link 2 Bass AR, Chakravarty E, Akl EA, Bingham CO, Calabrese L, Cappelli LC et al.. 2022 American College of Rheumatology Guideline for Vaccinations in Patients With Rheumatic and Musculoskeletal Diseases. Arthritis care & research 2023. link 3 Bass AR, Chakravarty E, Akl EA, Bingham CO, Calabrese L, Cappelli LC et al.. 2022 American College of Rheumatology Guideline for Vaccinations in Patients With Rheumatic and Musculoskeletal Diseases. Arthritis & rheumatology (Hoboken, N.J.) 2023. link

    Original source

    1. [1]
      Vaccination coverage among people who inject drugs: A systematic review. — Price O, Swanton R, Grebely J, Hajarizadeh B, Webb P, Peacock A et al. The International journal on drug policy (2024)
    2. [2]
      2022 American College of Rheumatology Guideline for Vaccinations in Patients With Rheumatic and Musculoskeletal Diseases. — Bass AR, Chakravarty E, Akl EA, Bingham CO, Calabrese L, Cappelli LC et al. Arthritis care & research (2023)
    3. [3]
      2022 American College of Rheumatology Guideline for Vaccinations in Patients With Rheumatic and Musculoskeletal Diseases. — Bass AR, Chakravarty E, Akl EA, Bingham CO, Calabrese L, Cappelli LC et al. Arthritis & rheumatology (Hoboken, N.J.) (2023)
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