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Cardiology100 papers

Atherosclerosis of left coronary artery main stem

Last edited: 4/10/2026

Overview

Atherosclerosis is a progressive disease process that begins in childhood and is the primary driver of cardiovascular and cerebrovascular diseases, which are leading causes of mortality worldwide 1. The increasing prevalence of modifiable cardiovascular risk factors in children and adolescents underscores the need for early prevention strategies 1.

Diagnosis

No diagnostic criteria or specific tests for atherosclerosis of the left coronary artery main stem were mentioned in the provided abstracts.

Management

No specific management strategies for atherosclerosis of the left coronary artery main stem were mentioned in the provided abstracts.

Special Populations

  • Atherosclerosis should be considered a disease with its roots in childhood, and primary prevention should begin from pregnancy and birth 1.
  • Early identification and management of specific cardiovascular risk factors in children and adolescents are crucial 1.

    • Key Recommendations

  • Cardiovascular prevention strategies should start early in life, beginning from pregnancy and birth 1. (Evidence: Expert opinion)
  • Two complementary levels of intervention should be considered: population-wide promotion of healthy diets and lifestyles, and early identification and management of specific cardiovascular risk factors in children and adolescents 1. (Evidence: Expert opinion)
  • Involvement of multiple stakeholders, including families, pediatricians, schools, healthcare professionals, policymakers, patient associations, and the media, is crucial for effective prevention interventions 1. (Evidence: Expert opinion)

    • References

    1 Genovesi S, Volpe R, Agnoletti D, Bellone S, Bona G, Casula M et al.. Cardiovascular Prevention in Children, Adolescents, and Young Adults. A Call-to-Action of the Italian Societies of Pediatrics (SIP), Hypertension (SIIA), Study of Atherosclerosis (SISA), and Cardiovascular Prevention (SIPREC). High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension 2026. link

    Original source

    1. [1]
      Cardiovascular Prevention in Children, Adolescents, and Young Adults. A Call-to-Action of the Italian Societies of Pediatrics (SIP), Hypertension (SIIA), Study of Atherosclerosis (SISA), and Cardiovascular Prevention (SIPREC). — Genovesi S, Volpe R, Agnoletti D, Bellone S, Bona G, Casula M et al. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension (2026)
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