Overview
Acute renocardiac syndrome is a complex clinical condition involving the simultaneous dysfunction of the heart and kidneys. This syndrome highlights the intricate relationship between these two vital organs and the potential for cross-organ injury in critical illness.Diagnosis
Management
Hemodynamic support using vasoactive agents is a mainstay in the management of pediatric fluid-refractory septic shock 1.
First-line vasoactive strategies for pediatric fluid-refractory septic shock include dopamine, epinephrine, or norepinephrine 1.Special Populations
Pediatrics: In pediatric fluid-refractory septic shock, pooled mortality for patients receiving a single vasoactive agent was 12% 1. Pooled mortality was 11% for dopamine, 17% for epinephrine, and 7% for norepinephrine 1.Key Recommendations
Vasoactive agent selection for pediatric fluid-refractory septic shock should consider available evidence on mortality 1. (Evidence: Moderate)
Dopamine, epinephrine, and norepinephrine are considered first-line vasoactive agents in pediatric fluid-refractory septic shock 1. (Evidence: Moderate)References
1 Marchetto L, Zanetto L, Comoretto RI, Padrin D, Menon K, Amigoni A et al.. OUTCOMES OF PEDIATRIC FLUID-REFRACTORY SEPTIC SHOCK ACCORDING TO DIFFERENT VASOACTIVE STRATEGIES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Shock (Augusta, Ga.) 2024. link