Management
In a randomized, triple-blind trial [PMID:26584456], application of standardized N. sativa seed oil (600 mg applied twice daily for 2 months) significantly reduced pain scores compared to baseline and placebo, with outcomes comparable to topical diclofenac.
The study [PMID:26584456] found no significant differences in pain scores between the Nigella sativa seed oil group and the diclofenac group at 1 and 2 months, indicating comparable effectiveness between the two treatments.
Complications
The clinical trial [PMID:26584456] reported no adverse effects observed in participants using Nigella sativa seed oil over the 2-month treatment period.
References
1 Huseini HF, Kianbakht S, Mirshamsi MH, Zarch AB. Effectiveness of Topical Nigella sativa Seed Oil in the Treatment of Cyclic Mastalgia: A Randomized, Triple-Blind, Active, and Placebo-Controlled Clinical Trial. Planta medica 2016. link
1 papers cited of 3 indexed.