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Epiploic appendagitis

Last edited: 4/15/2026

Overview

Epiploic appendagitis is a rare inflammatory condition characterized by the torsion or infarction of epiploic appendages, leading to localized abdominal pain, often mimicking other intra-abdominal pathologies 12.

Diagnosis

  • Clinical Presentation: Typically presents with acute, sharp abdominal pain localized to the affected area 12.
  • Imaging Findings: Abdominal CT often shows a well-defined, oval or round lesion with fat stranding and peripheral enhancement, indicative of an infarcted epiploic appendage 1.
  • Unusual Radiological Signs: Thickened folds in small bowel loops may occasionally be observed, though this association is rare 1.
  • Differential Diagnosis: Includes appendicitis, diverticulitis, and other causes of acute abdomen 12.
  • Management

  • Conservative Management: Most cases resolve with conservative treatment, including pain control and observation 12.
  • Pain Management: Analgesics such as NSAIDs or opioids as needed for pain relief 1.
  • Surgical Intervention: Reserved for cases with persistent symptoms, complications (e.g., abscess formation), or diagnostic uncertainty 2.
  • Special Populations

  • Pregnancy: Specific management considerations not detailed in provided abstracts 12.
  • Pediatrics: No specific cases or management strategies discussed in the abstracts 12.
  • Elderly: No distinct management differences noted; conservative treatment generally applies 12.
  • Comorbidities: Management approach may need adjustment based on underlying conditions, though specifics are not provided 12.
  • Key Recommendations

  • Initial Imaging with CT to confirm diagnosis through characteristic imaging findings (Evidence: Moderate 1).
  • Conservative Treatment as first-line management, including pain control, is recommended for most patients (Evidence: Moderate 12).
  • Surgical Consultation should be considered for patients with persistent symptoms or suspected complications (Evidence: Expert opinion 2).
  • References

    1 Desai HP, Tripodi J, Gold BM, Burakoff R. Infarction of an epiploic appendage. Review of the literature. Journal of clinical gastroenterology 1993. link 2 Schein M, Rosen A, Decker GA. Acute conditions affecting epiploic appendages. A report of 4 cases. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1987. link

    Original source

    1. [1]
      Infarction of an epiploic appendage. Review of the literature.Desai HP, Tripodi J, Gold BM, Burakoff R Journal of clinical gastroenterology (1993)
    2. [2]
      Acute conditions affecting epiploic appendages. A report of 4 cases.Schein M, Rosen A, Decker GA South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde (1987)

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