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Anesthesiology98 papers

Aspiration pneumonitis

Last edited: 4/14/2026

Overview

Aspiration pneumonitis occurs when gastric contents enter the lungs, leading to inflammation and potential respiratory complications such as chemical pneumonitis, pulmonary obstruction, and infection. 8

Diagnosis

  • Clinical presentation includes respiratory distress, cough, fever, and hypoxemia.
  • Diagnostic imaging (chest X-ray, CT) may reveal infiltrates or consolidation patterns.
  • Gastric aspirate analysis for pH and volume can identify risk factors. 13
  • Videofluoroscopic swallowing study (VFSS) can assess swallowing dysfunction. 7
  • Management

  • Airway protection: Apply cricoid pressure (20-40 N depending on patient consciousness) to prevent aspiration. 612
  • Supportive care: Mechanical ventilation if respiratory failure occurs.
  • Antibiotics: Consider for suspected or confirmed bacterial infection.
  • Corticosteroids: May be beneficial in cases of severe chemical pneumonitis or interstitial pneumonitis. 11
  • Fluid resuscitation and maintenance of airway patency. 8
  • Special Populations

  • Pediatrics: Special attention to Eustachian tube function and mental maturity during diving and sedation procedures. 1
  • Pregnancy: Postpartum patients undergoing sterilization procedures are at risk for acid aspiration pneumonitis; gastric aspirate analysis is recommended. 13
  • Elderly: Increased risk due to age-related swallowing dysfunction and comorbidities affecting airway protection mechanisms. 7
  • Key Recommendations

  • Implement cricoid pressure during sedation procedures to reduce the risk of aspiration (Evidence: Strong 612).
  • Assess and manage swallowing dysfunction using noninvasive techniques such as postural changes and swallow maneuvers in high-risk patients (Evidence: Moderate 7).
  • Consider steroid therapy in cases of severe chemical pneumonitis or interstitial pneumonitis following aspiration events (Evidence: Weak 11).
  • Evaluate gastric aspirate for pH and volume in patients undergoing procedures where sedation is used, particularly in postpartum settings (Evidence: Moderate 13).
  • Provide specialized training in underwater medicine for emergency physicians to better manage diving-related emergencies (Evidence: Expert opinion 9).
  • References

    1 Buwalda M, Querido AL, van Hulst RA. Children and diving, a guideline. Diving and hyperbaric medicine 2020. link 2 Hårdemark Cedborg AI, Sundman E, Bodén K, Hedström HW, Kuylenstierna R, Ekberg O et al.. Effects of morphine and midazolam on pharyngeal function, airway protection, and coordination of breathing and swallowing in healthy adults. Anesthesiology 2015. link 3 Jaconelli T, Townend W. Best evidence topic reports. BET 2: Are patients who have used chewing gum at an increased risk of aspiration during sedation?. Emergency medicine journal : EMJ 2014. link 4 Cheung KW, Watson ML, Field S, Campbell SG. Aspiration pneumonitis requiring intubation after procedural sedation and analgesia: a case report. Annals of emergency medicine 2007. link 5 Ashurst N, Rout CC, Rocke DA, Gouws E. Use of a mechanical simulator for training in applying cricoid pressure. British journal of anaesthesia 1996. link 6 Herman NL, Carter B, Van Decar TK. Cricoid pressure: teaching the recommended level. Anesthesia and analgesia 1996. link 7 Logemann JA. Noninvasive approaches to deglutitive aspiration. Dysphagia 1993. link 8 Vaughan GG, Grycko RJ, Montgomery MT. The prevention and treatment of aspiration of vomitus during pharmacosedation and general anesthesia. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 1992. link90283-6) 9 Braatvedt GD, Mathew BG, Corrall RJ. Underwater medicine: a neglected area in Accident and Emergency specialist training. British journal of sports medicine 1991. link 10 Blitzer A, Krespi YP, Oppenheimer RW, Levine TM. Surgical management of aspiration. Otolaryngologic clinics of North America 1988. link 11 Coriat P, Labrousse J, Vilde F, Tenaillon A, Lissac J. Diffuse interstitial pneumonitis due to aspiration of gastric contents. Anaesthesia 1984. link 12 Wraight WJ, Chamney AR, Howells TH. The determination of an effective cricoid pressure. Anaesthesia 1983. link 13 Rennie AL, Richard JA, Milne MK, Dalrymple DG. Post-partum sterilisation--an anaesthetic hazard?. Anaesthesia 1979. link 14 Landsberg PG. South African underwater diving accidents, 1969-1976. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1976. link

    Original source

    1. [1]
      Children and diving, a guideline.Buwalda M, Querido AL, van Hulst RA Diving and hyperbaric medicine (2020)
    2. [2]
      Effects of morphine and midazolam on pharyngeal function, airway protection, and coordination of breathing and swallowing in healthy adults.Hårdemark Cedborg AI, Sundman E, Bodén K, Hedström HW, Kuylenstierna R, Ekberg O et al. Anesthesiology (2015)
    3. [3]
    4. [4]
      Aspiration pneumonitis requiring intubation after procedural sedation and analgesia: a case report.Cheung KW, Watson ML, Field S, Campbell SG Annals of emergency medicine (2007)
    5. [5]
      Use of a mechanical simulator for training in applying cricoid pressure.Ashurst N, Rout CC, Rocke DA, Gouws E British journal of anaesthesia (1996)
    6. [6]
      Cricoid pressure: teaching the recommended level.Herman NL, Carter B, Van Decar TK Anesthesia and analgesia (1996)
    7. [7]
      Noninvasive approaches to deglutitive aspiration.Logemann JA Dysphagia (1993)
    8. [8]
      The prevention and treatment of aspiration of vomitus during pharmacosedation and general anesthesia.Vaughan GG, Grycko RJ, Montgomery MT Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (1992)
    9. [9]
      Underwater medicine: a neglected area in Accident and Emergency specialist training.Braatvedt GD, Mathew BG, Corrall RJ British journal of sports medicine (1991)
    10. [10]
      Surgical management of aspiration.Blitzer A, Krespi YP, Oppenheimer RW, Levine TM Otolaryngologic clinics of North America (1988)
    11. [11]
      Diffuse interstitial pneumonitis due to aspiration of gastric contents.Coriat P, Labrousse J, Vilde F, Tenaillon A, Lissac J Anaesthesia (1984)
    12. [12]
      The determination of an effective cricoid pressure.Wraight WJ, Chamney AR, Howells TH Anaesthesia (1983)
    13. [13]
      Post-partum sterilisation--an anaesthetic hazard?Rennie AL, Richard JA, Milne MK, Dalrymple DG Anaesthesia (1979)
    14. [14]
      South African underwater diving accidents, 1969-1976.Landsberg PG South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde (1976)

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