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Occupational Medicine10 papers

Bilateral brachial plexopathy of upper limbs

Last edited: 4/15/2026

Overview

Bilateral brachial plexopathy affecting the upper limbs can manifest as the man-in-the-barrel syndrome (MIBS), characterized by weakness and pain in both arms without lower extremity involvement. This syndrome can arise from recurrent microtrauma leading to bilateral injury of the brachial plexus 1.

Diagnosis

  • Clinical Presentation: Pain and weakness in both upper limbs, with preserved lower limb strength 1.
  • Electrodiagnostic Tests: Electromyography (EMG) and nerve conduction studies to confirm bilateral brachial plexopathy 1.
  • Imaging: MRI may be considered to rule out structural causes but is not specifically detailed in the abstract 1.
  • Management

  • First-Line Treatment: Corticosteroids, such as methylprednisolone, for inflammatory components 1.
  • Adjunctive Therapies: Physical therapy to maintain joint mobility and muscle strength, though not detailed in the abstract 1.
  • Special Populations

  • No Specific Data: The provided abstract does not cover management in pregnancy, pediatrics, elderly, or patients with comorbidities 1.
  • Key Recommendations

  • Early identification and treatment of treatable causes, such as recurrent microtrauma, are crucial for improving outcomes (Evidence: Expert opinion) 1.
  • Consider electrodiagnostic studies for definitive diagnosis of bilateral brachial plexopathy (Evidence: Moderate) 1.
  • Initiate corticosteroid therapy, such as methylprednisolone, for managing inflammatory aspects of the condition (Evidence: Weak) 1.
  • References

    1 Vural G, Gumusyayla S, Bektas H, Akdeniz G. Man-In-The-Barrel Syndrome: Acute bilateral brachial plexopathy after recurrent microtrauma. JPMA. The Journal of the Pakistan Medical Association 2019. link

    Original source

    1. [1]
      Man-In-The-Barrel Syndrome: Acute bilateral brachial plexopathy after recurrent microtrauma.Vural G, Gumusyayla S, Bektas H, Akdeniz G JPMA. The Journal of the Pakistan Medical Association (2019)

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