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Allergy & Immunology452 papers

Actinobacillus infection

Last edited: 4/15/2026

Overview

Actinobacillus infections are primarily caused by Actinobacillus species, notably Actinobacillus pleuropneumoniae and Actinobacillus suis, affecting pigs and rarely humans, leading to respiratory and systemic diseases [not directly covered in provided abstracts].

Diagnosis

  • Clinical Presentation: Symptoms include respiratory distress, fever, and localized infections [not directly covered in provided abstracts].
  • Laboratory Tests: Culture and sensitivity testing from affected tissues are crucial for diagnosis [not directly covered in provided abstracts].
  • Serological Testing: Specific serology may aid in confirming infections, though not detailed in provided abstracts.
  • Management

  • Antibiotics: First-line treatment often includes aminoglycosides or tetracyclines, though specific dosing is not provided in abstracts [not directly covered in provided abstracts].
  • Supportive Care: Includes respiratory support and management of complications [not directly covered in provided abstracts].
  • Special Populations

  • Pregnancy: Limited data; management focuses on supportive care and antibiotic therapy tailored to gestational safety [not directly covered in provided abstracts].
  • Pediatrics: Specific pediatric dosing and considerations are not detailed in provided abstracts [not directly covered in provided abstracts].
  • Elderly: Increased vigilance for complications and tailored antibiotic therapy based on renal function and comorbidities [not directly covered in provided abstracts].
  • Comorbidities: Management should consider interactions with existing conditions, though specifics are not provided [not directly covered in provided abstracts].
  • Key Recommendations

  • Culture and Sensitivity Testing: Essential for accurate diagnosis and guiding antibiotic therapy (Evidence: Expert opinion [not directly covered in provided abstracts]).
  • Antibiotic Therapy: Initiate with broad-spectrum antibiotics targeting common pathogens, adjusting based on culture results (Evidence: Expert opinion [not directly covered in provided abstracts]).
  • Monitor for Complications: Regular monitoring is crucial, especially in vulnerable populations like the elderly and those with comorbidities (Evidence: Expert opinion [not directly covered in provided abstracts]).
  • References

    1 Petit-Glatron MF, Benyahia F, Chambert R. Secretion of Bacillus subtilis levansucrase: a possible two-step mechanism. European journal of biochemistry 1987. link 2 Hofstad T. Immunochemistry of a cell wall polysaccharide isolated from Eubacterium saburreum, strain L49. Acta pathologica et microbiologica Scandinavica. Section B, Microbiology 1975. link 3 Knox KW, Wicken AJ. Serological studies on the teichoic acids of Lactobacillus plantarum. Infection and immunity 1972. link

    Original source

    1. [1]
      Secretion of Bacillus subtilis levansucrase: a possible two-step mechanism.Petit-Glatron MF, Benyahia F, Chambert R European journal of biochemistry (1987)
    2. [2]
      Immunochemistry of a cell wall polysaccharide isolated from Eubacterium saburreum, strain L49.Hofstad T Acta pathologica et microbiologica Scandinavica. Section B, Microbiology (1975)
    3. [3]
      Serological studies on the teichoic acids of Lactobacillus plantarum.Knox KW, Wicken AJ Infection and immunity (1972)

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