Overview
Infection related to nephrostomy catheter placement, particularly in the context of percutaneous nephrolithotomy (PCNL), is a significant concern. Antibiotic prophylaxis is employed to reduce the incidence of infection-related complications.Management
A single dose of preventive antibiotics is generally sufficient to reduce infection-related complications in PCNL 1.
Extended-dose antibiotic prophylaxis may be beneficial in high-risk patients to further reduce complications such as systemic inflammatory response syndrome (SIRS) 1.Key Recommendations
Single-dose antibiotic prophylaxis is effective for reducing infection-related complications in percutaneous nephrolithotomy (PCNL) 1. (Evidence: Strong)
Extended-dose antibiotic prophylaxis may be required in high-risk patients undergoing PCNL to lower the rate of SIRS 1. (Evidence: Moderate)References
1 Jung HD, Cho KS, Moon YJ, Chung DY, Kang DH, Lee JY. Antibiotic prophylaxis for percutaneous nephrolithotomy: An updated systematic review and meta-analysis. PloS one 2022. link