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Congenital sequestration of lung

Last edited: 4/22/2026

Overview

Congenital sequestration of lung is a rare congenital anomaly characterized by a non-functioning lung tissue mass supplied by the systemic circulation rather than the pulmonary arteries. It can occur with other congenital anomalies, such as situs inversus totalis 1.

Diagnosis

  • Imaging: High-resolution CT or MRI showing a non-bronchial vascular supply from the aorta or its branches 2.
  • Angiography: Essential for delineating the anomalous systemic arterial supply and identifying the drainage pathway 2.
  • Situs Inversus Assessment: Consideration in patients presenting with unusual anatomical configurations 1.
  • Management

  • Surgical Resection: First-line treatment for definitive management, often via lobectomy or segmentectomy 2.
  • Preoperative Imaging: Detailed imaging to plan surgical approach and understand vascular anatomy 2.
  • Postoperative Care: Standard postoperative monitoring and management for respiratory and circulatory stability 2.
  • Special Populations

  • Pediatrics: Surgical intervention is typically recommended early to prevent complications such as recurrent infections 2.
  • Comorbidities: Presence of situs inversus totalis does not alter the primary management approach but may complicate surgical planning 1.
  • Key Recommendations

  • Surgical resection is recommended for definitive treatment of intralobar pulmonary sequestration (Evidence: Strong 2).
  • Detailed preoperative imaging, including angiography, is crucial for surgical planning (Evidence: Moderate 2).
  • Consider anatomical variations such as situs inversus totalis during evaluation to guide surgical approach (Evidence: Expert opinion 1).
  • References

    1 Sankar NM, Kumar S, Natarajan S, Kumar S, Krishnan R, Jawale Y. Intralobar sequestration with situs inversus totalis. Asian cardiovascular & thoracic annals 2015. link 2 Gupta SK, Abraham KA, Ganesh KM. Intralobar sequestration of upper lobe of right lung--case reports. Angiology 1988. link

    Original source

    1. [1]
      Intralobar sequestration with situs inversus totalis.Sankar NM, Kumar S, Natarajan S, Kumar S, Krishnan R, Jawale Y Asian cardiovascular & thoracic annals (2015)
    2. [2]
      Intralobar sequestration of upper lobe of right lung--case reports.Gupta SK, Abraham KA, Ganesh KM Angiology (1988)

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